SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 10 ASP A  93
ASP A 236
GLU A 237
ARG A  69
ARG A 239
 None
 1.32A 1nd4A-3gg9A:
0.0		 1nd4A-3gg9A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		4 / 4 SER A  91
ASP A  99
ARG A  72
ASP A  76
 None
 1.45A 2bm9C-3gg9A:
4.1		 2bm9C-3gg9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		4 / 6 LEU A 167
VAL A 257
ILE A 174
ARG A 249
 None
 1.00A 2hyyA-3gg9A:
undetectable		 2hyyA-3gg9A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 LEU A  61
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 0.92A 2nxeA-3gg9A:
7.9		 2nxeA-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 LEU A  61
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 0.91A 2nxeB-3gg9A:
undetectable		 2nxeB-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 11 LEU A 221
PHE A 222
ILE A 241
HIS A 231
VAL A 128
 None
 1.30A 3aqiA-3gg9A:
3.6		 3aqiA-3gg9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 LEU A 221
PHE A 222
ILE A 241
HIS A 231
VAL A 128
 None
 1.34A 3aqiB-3gg9A:
6.0		 3aqiB-3gg9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		6 / 12 LEU A  61
VAL A 340
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 1.10A 3cjtC-3gg9A:
8.3		 3cjtC-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		6 / 12 LEU A  61
VAL A 340
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 1.08A 3cjtG-3gg9A:
8.3		 3cjtG-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		6 / 12 LEU A  61
VAL A 340
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 1.09A 3cjtK-3gg9A:
8.4		 3cjtK-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		6 / 12 LEU A  61
VAL A 340
LEU A 111
ASP A  99
LEU A  81
LEU A  78
 None
 1.08A 3cjtO-3gg9A:
8.3		 3cjtO-3gg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 GLY A 277
GLY A 280
PHE A 256
SER A 154
ALA A 273
 None
 1.20A 3dh0A-3gg9A:
5.4		 3dh0A-3gg9A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		3 / 3 ASP A 246
PHE A 175
SER A 217
 None
 0.61A 3i5uB-3gg9A:
6.5		 3i5uB-3gg9A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 THR A 259
SER A 260
LEU A 172
VAL A 195
VAL A 184
 None
GOL  A 364 (-3.6A)
None
None
None
 1.43A 3u9fB-3gg9A:
undetectable
3u9fC-3gg9A:
undetectable		 3u9fB-3gg9A:
20.88
3u9fC-3gg9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 11 THR A 259
SER A 260
LEU A 172
VAL A 195
VAL A 184
 None
GOL  A 364 (-3.6A)
None
None
None
 1.50A 3u9fN-3gg9A:
undetectable
3u9fO-3gg9A:
undetectable		 3u9fN-3gg9A:
20.88
3u9fO-3gg9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		4 / 7 ILE A  84
THR A  44
LEU A  51
VAL A  55
 None
 0.70A 3ua5B-3gg9A:
undetectable		 3ua5B-3gg9A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 LEU A 221
PHE A 222
ILE A 241
HIS A 231
VAL A 128
 None
 1.34A 3w1wB-3gg9A:
undetectable		 3w1wB-3gg9A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 SER A 225
LEU A 228
TRP A 198
GLY A 173
VAL A 195
 None
 1.45A 5jo9A-3gg9A:
3.4		 5jo9A-3gg9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		4 / 7 LEU A 234
ILE A  98
GLU A  66
ASP A  93
 None
 1.03A 5n5dA-3gg9A:
5.1		 5n5dA-3gg9A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 10 LEU A 274
GLY A 277
VAL A 244
LEU A 247
ARG A 249
 None
 1.15A 5o96E-3gg9A:
2.3
5o96F-3gg9A:
undetectable		 5o96E-3gg9A:
22.60
5o96F-3gg9A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN
(Ralstonia
solanacearum) 		5 / 12 ALA A 121
PRO A 120
GLY A 311
GLY A 188
LEU A 172
 None
 1.10A 5wwsA-3gg9A:
5.4		 5wwsA-3gg9A:
22.37