SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3gge PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Homo
sapiens) 		5 / 10 LEU A 182
VAL A 178
ILE A 165
GLU A 115
LEU A 195
 None
 1.10A 1cqpA-3ggeA:
undetectable
1cqpB-3ggeA:
undetectable		 1cqpA-3ggeA:
22.22
1cqpB-3ggeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3gge PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Homo
sapiens) 		3 / 3 MET A 193
VAL A 178
GLU A 163
 None
 0.91A 3c6gA-3ggeA:
undetectable		 3c6gA-3ggeA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3gge PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Homo
sapiens) 		5 / 10 ASP A 177
ILE A 170
GLY A 172
GLY A 137
ILE A 131
 None
 0.91A 3em4V-3ggeA:
undetectable		 3em4V-3ggeA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3gge PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Homo
sapiens) 		3 / 3 VAL A 149
GLY A 147
LYS A 145
 None
 0.78A 4k50A-3ggeA:
undetectable		 4k50A-3ggeA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gge PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
(Homo
sapiens) 		5 / 10 LEU A 129
LEU A 182
LEU A 185
ILE A 141
VAL A 118
 None
 1.15A 4mk4A-3ggeA:
undetectable		 4mk4A-3ggeA:
13.09