SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ggy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.44A 1nsiA-3ggyA:
undetectable
1nsiB-3ggyA:
undetectable		 1nsiA-3ggyA:
17.78
1nsiB-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.47A 1nsiA-3ggyA:
undetectable
1nsiB-3ggyA:
undetectable		 1nsiA-3ggyA:
17.78
1nsiB-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.45A 1nsiC-3ggyA:
undetectable
1nsiD-3ggyA:
undetectable		 1nsiC-3ggyA:
17.78
1nsiD-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.48A 1nsiC-3ggyA:
undetectable
1nsiD-3ggyA:
undetectable		 1nsiC-3ggyA:
17.78
1nsiD-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 116
ILE A 136
ILE A 145
LEU A  12
 None
 0.92A 1zgyA-3ggyA:
undetectable		 1zgyA-3ggyA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.48A 2nsiA-3ggyA:
undetectable
2nsiB-3ggyA:
undetectable		 2nsiA-3ggyA:
17.78
2nsiB-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.47A 2nsiA-3ggyA:
undetectable
2nsiB-3ggyA:
undetectable		 2nsiA-3ggyA:
17.78
2nsiB-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.49A 2nsiC-3ggyA:
undetectable
2nsiD-3ggyA:
undetectable		 2nsiC-3ggyA:
17.78
2nsiD-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.48A 2nsiC-3ggyA:
undetectable
2nsiD-3ggyA:
undetectable		 2nsiC-3ggyA:
17.78
2nsiD-3ggyA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.44A 3e7gA-3ggyA:
undetectable
3e7gB-3ggyA:
undetectable		 3e7gA-3ggyA:
17.41
3e7gB-3ggyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.43A 3e7gA-3ggyA:
undetectable
3e7gB-3ggyA:
undetectable		 3e7gA-3ggyA:
17.41
3e7gB-3ggyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.46A 3e7gC-3ggyA:
undetectable
3e7gD-3ggyA:
undetectable		 3e7gC-3ggyA:
17.41
3e7gD-3ggyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.43A 3e7gC-3ggyA:
undetectable
3e7gD-3ggyA:
undetectable		 3e7gC-3ggyA:
17.41
3e7gD-3ggyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 151
ILE A 145
TYR A 114
ILE A 113
 None
 0.84A 3hgxA-3ggyA:
undetectable		 3hgxA-3ggyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 GLU A  71
LEU A  23
GLN A  30
HIS A  66
 None
 1.27A 3pp1A-3ggyA:
undetectable		 3pp1A-3ggyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 GLU A  71
LEU A  73
GLN A  30
HIS A  66
 None
 1.21A 3pp1A-3ggyA:
undetectable		 3pp1A-3ggyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 158
LYS A 157
PRO A 161
 None
 1.23A 4dv1L-3ggyA:
undetectable		 4dv1L-3ggyA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 110
ILE A  90
PHE A 140
GLU A  94
 None
 1.41A 4nosC-3ggyA:
undetectable
4nosD-3ggyA:
undetectable		 4nosC-3ggyA:
17.95
4nosD-3ggyA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3ggy INCREASED SODIUM
TOLERANCE PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 140
GLU A  94
ARG A 110
ILE A  90
 None
 1.42A 4nosC-3ggyA:
undetectable
4nosD-3ggyA:
undetectable		 4nosC-3ggyA:
17.95
4nosD-3ggyA:
17.95