SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 9 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 1.03A 1hpvA-3gh8A:
undetectable		 1hpvA-3gh8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.79A 2avsA-3gh8A:
undetectable		 2avsA-3gh8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.74A 2avvA-3gh8A:
undetectable		 2avvA-3gh8A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.71A 2avvE-3gh8A:
undetectable		 2avvE-3gh8A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.85A 2f8gB-3gh8A:
undetectable		 2f8gB-3gh8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.77A 2nmyB-3gh8A:
undetectable		 2nmyB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.84A 2nmzA-3gh8A:
undetectable		 2nmzA-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.86A 2nmzB-3gh8A:
undetectable		 2nmzB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.84A 2o4lB-3gh8A:
undetectable		 2o4lB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.79A 2pymB-3gh8A:
undetectable		 2pymB-3gh8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 2pynB-3gh8A:
undetectable		 2pynB-3gh8A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.82A 2q63A-3gh8A:
undetectable		 2q63A-3gh8A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.82A 2q63B-3gh8A:
undetectable		 2q63B-3gh8A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 2q64A-3gh8A:
undetectable		 2q64A-3gh8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.76A 2q64B-3gh8A:
undetectable		 2q64B-3gh8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.77A 2qakA-3gh8A:
undetectable		 2qakA-3gh8A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 3bvbA-3gh8A:
undetectable		 3bvbA-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.77A 3d1xB-3gh8A:
undetectable		 3d1xB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 10 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.87A 3ekpD-3gh8A:
undetectable		 3ekpD-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 243
LEU A 246
ARG A 249
PHE A 191
THR A 132
 None
 1.33A 3gwuA-3gh8A:
undetectable		 3gwuA-3gh8A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.76A 3jvyB-3gh8A:
undetectable		 3jvyB-3gh8A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.79A 3jw2B-3gh8A:
undetectable		 3jw2B-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.72A 3k4vA-3gh8A:
undetectable		 3k4vA-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.75A 3k4vB-3gh8A:
undetectable		 3k4vB-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 3k4vD-3gh8A:
undetectable		 3k4vD-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.79A 3ndtA-3gh8A:
undetectable		 3ndtA-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.78A 3ndtB-3gh8A:
undetectable		 3ndtB-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.86A 3ndtC-3gh8A:
undetectable		 3ndtC-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.75A 3nduA-3gh8A:
undetectable		 3nduA-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.78A 3nduB-3gh8A:
undetectable		 3nduB-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.83A 3nduC-3gh8A:
undetectable		 3nduC-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.83A 3nduD-3gh8A:
undetectable		 3nduD-3gh8A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.79A 3nu5A-3gh8A:
undetectable		 3nu5A-3gh8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.73A 3nu5B-3gh8A:
undetectable		 3nu5B-3gh8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.91A 3oxcB-3gh8A:
undetectable		 3oxcB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 3oxxA-3gh8A:
undetectable		 3oxxA-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.76A 3pwrB-3gh8A:
undetectable		 3pwrB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 TYR A 208
LEU A 255
LYS A 254
 None
 0.63A 3sueD-3gh8A:
undetectable		 3sueD-3gh8A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 LYS A 254
VAL A 194
HIS A 195
 None
 1.21A 3tj7A-3gh8A:
undetectable		 3tj7A-3gh8A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.80A 3tkgA-3gh8A:
undetectable		 3tkgA-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.76A 3tkgB-3gh8A:
undetectable		 3tkgB-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.88A 3tkgD-3gh8A:
undetectable		 3tkgD-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.81A 3tkwB-3gh8A:
undetectable		 3tkwB-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.82A 3tl9A-3gh8A:
undetectable		 3tl9A-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.82A 3tl9B-3gh8A:
undetectable		 3tl9B-3gh8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.78A 4jecA-3gh8A:
undetectable		 4jecA-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.84A 4jecB-3gh8A:
undetectable		 4jecB-3gh8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.12A 4qvlV-3gh8A:
undetectable
4qvlb-3gh8A:
undetectable		 4qvlV-3gh8A:
20.54
4qvlb-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.12A 4qvlH-3gh8A:
undetectable
4qvlN-3gh8A:
undetectable		 4qvlH-3gh8A:
20.54
4qvlN-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 10 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.14A 4qvvH-3gh8A:
undetectable
4qvvN-3gh8A:
0.0		 4qvvH-3gh8A:
20.54
4qvvN-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.09A 4qvyV-3gh8A:
0.0
4qvyb-3gh8A:
1.0		 4qvyV-3gh8A:
20.54
4qvyb-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.10A 4qvyH-3gh8A:
0.0
4qvyN-3gh8A:
0.0		 4qvyH-3gh8A:
20.54
4qvyN-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.14A 4qw0V-3gh8A:
undetectable
4qw0b-3gh8A:
undetectable		 4qw0V-3gh8A:
20.54
4qw0b-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.15A 4qw0H-3gh8A:
undetectable
4qw0N-3gh8A:
undetectable		 4qw0H-3gh8A:
20.54
4qw0N-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.14A 5bxnV-3gh8A:
undetectable
5bxnb-3gh8A:
undetectable		 5bxnV-3gh8A:
20.42
5bxnb-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.14A 5bxnH-3gh8A:
undetectable
5bxnN-3gh8A:
undetectable		 5bxnH-3gh8A:
20.42
5bxnN-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 11 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.14A 5d0xV-3gh8A:
undetectable
5d0xb-3gh8A:
undetectable		 5d0xV-3gh8A:
20.54
5d0xb-3gh8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
SER A 124
VAL A 213
ALA A 119
ALA A 216
 None
 1.20A 5tzoB-3gh8A:
undetectable		 5tzoB-3gh8A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 LEU A 258
THR A 174
ASN A 175
 None
TYI  A 302 ( 3.7A)
None
 0.66A 6baaE-3gh8A:
undetectable		 6baaE-3gh8A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 LEU A 258
THR A 174
ASN A 175
 None
TYI  A 302 ( 3.7A)
None
 0.66A 6baaF-3gh8A:
undetectable		 6baaF-3gh8A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 LEU A 258
THR A 174
ASN A 175
 None
TYI  A 302 ( 3.7A)
None
 0.66A 6baaG-3gh8A:
undetectable		 6baaG-3gh8A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		3 / 3 LEU A 258
THR A 174
ASN A 175
 None
TYI  A 302 ( 3.7A)
None
 0.67A 6baaH-3gh8A:
undetectable		 6baaH-3gh8A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.99A 6dh6A-3gh8A:
undetectable		 6dh6A-3gh8A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.80A 6difB-3gh8A:
undetectable		 6difB-3gh8A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 LEU A 256
GLY A 218
ILE A 116
GLY A 120
ILE A 190
 None
 0.78A 6dilB-3gh8A:
undetectable		 6dilB-3gh8A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.12A 6hwdV-3gh8A:
undetectable
6hwdb-3gh8A:
undetectable		 6hwdV-3gh8A:
14.23
6hwdb-3gh8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3gh8 IODOTYROSINE
DEHALOGENASE 1
(Mus
musculus) 		5 / 12 SER A 214
THR A 231
THR A 233
THR A 234
THR A 235
 None
None
FMN  A 301 (-4.4A)
FMN  A 301 (-4.5A)
FMN  A 301 (-3.6A)
 1.12A 6hwdH-3gh8A:
undetectable
6hwdN-3gh8A:
undetectable		 6hwdH-3gh8A:
14.23
6hwdN-3gh8A:
14.63