SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ghf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC
(Salmonella
enterica) 		4 / 4 ILE A  28
LEU A  86
VAL A  52
ILE A  50
 None
 0.87A 1fm6D-3ghfA:
undetectable		 1fm6D-3ghfA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC
(Salmonella
enterica) 		4 / 8 VAL A  52
VAL A  78
LEU A  20
HIS A  65
 None
 0.98A 2ddwA-3ghfA:
undetectable		 2ddwA-3ghfA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC
(Salmonella
enterica) 		4 / 8 ILE A  50
ILE A  75
ASN A  60
VAL A  59
 None
None
CIT  A 201 (-4.7A)
CIT  A 201 (-3.8A)
 0.55A 2nniA-3ghfA:
undetectable		 2nniA-3ghfA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC
(Salmonella
enterica) 		4 / 7 LEU A  55
GLU A  22
LEU A  20
ILE A  28
 CIT  A 201 (-3.6A)
CIT  A 201 (-2.8A)
None
None
 0.82A 3s56B-3ghfA:
undetectable		 3s56B-3ghfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC
(Salmonella
enterica) 		4 / 7 ILE A  90
ILE A  75
GLU A  63
VAL A  59
 None
None
CIT  A 201 (-3.6A)
CIT  A 201 (-3.8A)
 0.83A 3ua5B-3ghfA:
undetectable		 3ua5B-3ghfA:
14.02