SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ghp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		4 / 5 LEU A 120
LEU A  76
LEU A 105
GLY A  41
 None
 0.84A 1a4lC-3ghpA:
undetectable		 1a4lC-3ghpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		3 / 3 ASN A  45
LEU A  98
HIS A  89
 None
 0.68A 2q6fB-3ghpA:
undetectable		 2q6fB-3ghpA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		4 / 6 TYR A  11
GLY A 118
THR A  13
GLU A  74
 None
 0.79A 3fpjA-3ghpA:
undetectable		 3fpjA-3ghpA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		5 / 12 ILE A  46
ALA A  29
LEU A  53
GLN A  54
VAL A 136
 None
 1.14A 3ix9A-3ghpA:
undetectable		 3ix9A-3ghpA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		5 / 10 LEU A 120
MET A 143
GLY A 146
ILE A 147
VAL A  31
 None
 1.07A 3ogpA-3ghpA:
undetectable		 3ogpA-3ghpA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		5 / 11 ALA A 121
SER A  72
THR A 151
PHE A 153
ARG A 100
 None
 1.17A 4bb2A-3ghpA:
undetectable
4bb2B-3ghpA:
undetectable		 4bb2A-3ghpA:
19.14
4bb2B-3ghpA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		5 / 12 ILE A  27
ILE A  95
PHE A 125
VAL A  44
LEU A  98
 None
 0.96A 5mueA-3ghpA:
undetectable		 5mueA-3ghpA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3ghp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		4 / 6 ALA A  55
SER A  68
GLY A  87
PHE A 137
 None
 0.90A 6f8cA-3ghpA:
undetectable		 6f8cA-3ghpA:
14.41