SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		3 / 3 TRP A 111
ALA A  99
VAL A 107
 None
None
PE4  A6061 (-4.6A)
 0.91A 1c4dA-3gk6A:
undetectable
1c4dB-3gk6A:
undetectable		 1c4dA-3gk6A:
9.43
1c4dB-3gk6A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		3 / 3 ALA A  99
VAL A 107
TRP A 111
 None
PE4  A6061 (-4.6A)
None
 0.86A 1c4dC-3gk6A:
undetectable
1c4dD-3gk6A:
undetectable		 1c4dC-3gk6A:
9.43
1c4dD-3gk6A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		3 / 3 TRP A 111
ALA A  99
VAL A 107
 None
None
PE4  A6061 (-4.6A)
 0.81A 1c4dC-3gk6A:
undetectable
1c4dD-3gk6A:
undetectable		 1c4dC-3gk6A:
9.43
1c4dD-3gk6A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		5 / 11 ASP A 132
ALA A 147
VAL A  95
VAL A 114
ILE A 146
 None
 1.03A 3lzvB-3gk6A:
undetectable		 3lzvB-3gk6A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		4 / 6 ALA A  71
VAL A  69
TYR A  56
VAL A 107
 None
None
None
PE4  A6061 (-4.6A)
 0.93A 5eclA-3gk6A:
undetectable		 5eclA-3gk6A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3gk6 INTEGRON CASSETTE
PROTEIN VCH_CASS2
(Vibrio
cholerae) 		5 / 8 LEU A  34
VAL A  16
VAL A  69
PHE A  67
ASP A  22
 None
 1.47A 5y9mA-3gk6A:
undetectable		 5y9mA-3gk6A:
17.05