SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		4 / 5 VAL A  56
GLN A  80
PHE A 136
ARG A 140
 None
 0.96A 3bjwE-3gl3A:
undetectable		 3bjwE-3gl3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		4 / 6 VAL A  56
GLN A  80
PHE A 136
ARG A 140
 None
 1.06A 3bjwF-3gl3A:
undetectable		 3bjwF-3gl3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		5 / 12 ALA A  35
GLY A 142
GLY A  32
ASP A  30
LEU A  29
 None
 1.26A 3ou7A-3gl3A:
undetectable		 3ou7A-3gl3A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		5 / 12 ALA A  35
GLY A 142
GLY A  32
ASP A  30
LEU A  29
 None
 1.23A 3ou7D-3gl3A:
undetectable		 3ou7D-3gl3A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		5 / 11 THR A 123
LEU A  59
VAL A  91
LEU A  40
VAL A  46
 None
 1.21A 3tbgA-3gl3A:
undetectable		 3tbgA-3gl3A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		5 / 10 THR A 123
LEU A  59
VAL A  91
LEU A  40
VAL A  46
 None
 1.18A 3tbgC-3gl3A:
undetectable		 3tbgC-3gl3A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3gl3 PUTATIVE
THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Chlorobaculum
tepidum) 		3 / 3 LYS A  82
GLU A 160
TRP A  75
 None
 1.49A 3v4tH-3gl3A:
undetectable		 3v4tH-3gl3A:
16.39