SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		3 / 3 ARG A 189
ARG A 172
ARG A   2
 None
 1.10A 1l7fA-3gl5A:
undetectable		 1l7fA-3gl5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		3 / 3 ARG A 189
ARG A 172
ARG A   2
 None
 1.09A 1l7hA-3gl5A:
undetectable		 1l7hA-3gl5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		4 / 4 ARG A  20
LEU A  77
ASN A  76
VAL A  16
 None
 1.40A 1lqtA-3gl5A:
undetectable		 1lqtA-3gl5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		4 / 4 ARG A  20
LEU A  77
ASN A  76
VAL A  16
 None
 1.41A 1lquA-3gl5A:
undetectable		 1lquA-3gl5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		5 / 12 LEU A 101
LEU A 104
LEU A 107
ALA A 108
ILE A   9
 None
 0.83A 1s9pC-3gl5A:
undetectable		 1s9pC-3gl5A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		3 / 3 ARG A   2
ARG A  39
ARG A 189
 None
 0.96A 2jb7A-3gl5A:
undetectable
2jb7B-3gl5A:
undetectable
2jb7C-3gl5A:
undetectable		 2jb7A-3gl5A:
21.46
2jb7B-3gl5A:
21.46
2jb7C-3gl5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		3 / 3 ARG A  39
ARG A 189
ARG A   2
 None
 1.00A 2jb7A-3gl5A:
undetectable
2jb7B-3gl5A:
undetectable
2jb7C-3gl5A:
undetectable		 2jb7A-3gl5A:
21.46
2jb7B-3gl5A:
21.46
2jb7C-3gl5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		3 / 3 ARG A 189
ARG A   2
ARG A  39
 None
 0.99A 2jb7A-3gl5A:
undetectable
2jb7B-3gl5A:
undetectable
2jb7C-3gl5A:
undetectable		 2jb7A-3gl5A:
21.46
2jb7B-3gl5A:
21.46
2jb7C-3gl5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		4 / 5 TYR A 122
ILE A   9
LEU A 117
LEU A 105
 None
 1.18A 2zb7A-3gl5A:
undetectable		 2zb7A-3gl5A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		5 / 12 GLY A 124
ALA A 120
PHE A 126
ARG A  93
VAL A 132
 NA  A 301 (-4.7A)
None
None
ACT  A 302 (-2.6A)
NA  A 301 ( 4.9A)
 1.16A 4azwA-3gl5A:
undetectable		 4azwA-3gl5A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		5 / 12 PHE A 185
PHE A  21
LEU A 118
SER A   7
TYR A 122
 None
 1.39A 4qb9E-3gl5A:
undetectable		 4qb9E-3gl5A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		4 / 5 LEU A 157
LEU A 117
THR A  98
ARG A  89
 None
 1.08A 6ew0F-3gl5A:
undetectable		 6ew0F-3gl5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		4 / 6 LEU A 157
LEU A 117
THR A  98
ARG A  89
 None
 1.08A 6ew0G-3gl5A:
undetectable		 6ew0G-3gl5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3gl5 PUTATIVE DSBA
OXIDOREDUCTASE
SCO1869
(Streptomyces
coelicolor) 		5 / 10 VAL A 153
ALA A 150
LEU A 157
LEU A 101
LEU A 104
 None
 1.03A 6f6nA-3gl5A:
undetectable
6f6nB-3gl5A:
undetectable		 6f6nA-3gl5A:
17.54
6f6nB-3gl5A:
17.13