SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gla'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.81A 1hshA-3glaA:
undetectable		 1hshA-3glaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.76A 1hshC-3glaA:
undetectable		 1hshC-3glaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 9 ASP A 118
ASP A 116
GLY A  76
ILE A  77
ILE A 133
 None
 1.02A 1hxwA-3glaA:
undetectable		 1hxwA-3glaA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 TRP A  42
VAL A  43
PRO A  44
 None
 0.98A 1rg1A-3glaA:
undetectable		 1rg1A-3glaA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 TRP A  42
VAL A  43
PRO A  44
 None
 0.97A 1rh0A-3glaA:
undetectable		 1rh0A-3glaA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 116
ILE A 120
ARG A 132
ILE A 131
ALA A 115
 None
None
PO4  A   1 (-3.1A)
None
None
 1.21A 3ohtA-3glaA:
undetectable
3ohtB-3glaA:
undetectable		 3ohtA-3glaA:
14.60
3ohtB-3glaA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 9 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.77A 3s45A-3glaA:
undetectable		 3s45A-3glaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.71A 3s54A-3glaA:
undetectable		 3s54A-3glaA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.69A 3s54B-3glaA:
undetectable		 3s54B-3glaA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 9 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.91A 3s56B-3glaA:
undetectable		 3s56B-3glaA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 ARG A  84
ARG A 101
TRP A  42
 None
 1.48A 4b7nA-3glaA:
undetectable		 4b7nA-3glaA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 ARG A  84
ARG A 101
TRP A  42
 None
 1.48A 4cpzC-3glaA:
undetectable		 4cpzC-3glaA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 ARG A  84
ARG A 101
TRP A  42
 None
 1.49A 4cpzE-3glaA:
undetectable		 4cpzE-3glaA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 ARG A  84
ARG A 101
TRP A  42
 None
 1.50A 4cpzF-3glaA:
undetectable		 4cpzF-3glaA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 ARG A  84
ARG A 101
TRP A  42
 None
 1.43A 4cpzG-3glaA:
undetectable		 4cpzG-3glaA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		3 / 3 LYS A  85
ILE A  64
ILE A  69
 None
 0.67A 4y0qA-3glaA:
undetectable		 4y0qA-3glaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		4 / 6 GLU A  51
GLY A 127
ARG A 125
GLY A 124
 PO4  A   1 ( 4.8A)
None
None
None
 0.87A 5cdnC-3glaA:
undetectable
5cdnD-3glaA:
undetectable		 5cdnC-3glaA:
12.64
5cdnD-3glaA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		4 / 6 GLU A  51
GLY A 127
ARG A 125
GLY A 124
 PO4  A   1 ( 4.8A)
None
None
None
 0.89A 5cdnT-3glaA:
undetectable
5cdnU-3glaA:
undetectable		 5cdnT-3glaA:
12.64
5cdnU-3glaA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3gla LOW MOLECULAR WEIGHT
HEAT SHOCK PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 118
GLY A  76
ILE A  77
ILE A 131
ILE A 120
 None
 0.68A 5e5jA-3glaA:
undetectable		 5e5jA-3glaA:
24.11