SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3glb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 ILE A 285
ILE A  94
PHE A 144
ASP A 277
LEU A 135
 None
 1.01A 1qhyA-3glbA:
undetectable		 1qhyA-3glbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 135
ALA A 272
ASP A 141
ILE A 109
LEU A 105
 None
 1.15A 1tw4A-3glbA:
undetectable		 1tw4A-3glbA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		7 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.52A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.56A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.93A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		7 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.50A 2f78B-3glbA:
29.8		 2f78B-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.56A 2f78B-3glbA:
29.8		 2f78B-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.91A 2f78B-3glbA:
29.8		 2f78B-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		7 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.29A 2f7aA-3glbA:
29.1		 2f7aA-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		7 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.69A 2f7aB-3glbA:
31.9		 2f7aB-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 6 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.57A 2f8dA-3glbA:
20.7		 2f8dA-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 6 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.94A 2f8dA-3glbA:
20.7		 2f8dA-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		8 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.6A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.46A 2f8dA-3glbA:
29.9		 2f8dA-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		8 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
 GOL  A   2 (-4.3A)
GOL  A   2 (-3.6A)
GOL  A   2 (-3.7A)
None
None
None
None
GOL  A   2 (-4.9A)
 0.51A 2f8dB-3glbA:
31.0		 2f8dB-3glbA:
54.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 105
LEU A 111
GLN A 115
PHE A 144
LEU A 142
 None
 1.34A 2w8yA-3glbA:
undetectable		 2w8yA-3glbA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 ALA A 134
ILE A 132
ARG A 274
GLY A 143
 None
 0.99A 3v4tH-3glbA:
undetectable		 3v4tH-3glbA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 6 LEU A 174
LEU A 166
ILE A 242
MET A 192
 None
 0.89A 4do3B-3glbA:
4.1		 4do3B-3glbA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 221
ALA A 167
ILE A 188
LEU A 214
GLY A 215
 None
 1.20A 4l9qB-3glbA:
undetectable		 4l9qB-3glbA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 142
VAL A 273
ILE A 282
ILE A 285
ALA A 287
 None
 1.03A 4ltwA-3glbA:
undetectable		 4ltwA-3glbA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 8 ILE A 227
GLU A 226
ILE A 242
LEU A 194
 CCU  A   3 ( 3.7A)
None
None
None
 0.85A 4mj8A-3glbA:
undetectable		 4mj8A-3glbA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 10 LEU A 271
ILE A 108
LEU A 105
LEU A 286
PHE A 144
 None
 1.06A 4odoA-3glbA:
undetectable		 4odoA-3glbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 10 LEU A 271
ILE A 108
LEU A 105
LEU A 286
PHE A 144
 None
 1.02A 4odoB-3glbA:
undetectable		 4odoB-3glbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 10 LEU A 271
ILE A 108
LEU A 105
LEU A 286
PHE A 144
 None
 1.06A 4odoC-3glbA:
undetectable		 4odoC-3glbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 271
GLY A 145
GLN A 131
LEU A 135
ILE A 302
 None
 1.33A 4p6xE-3glbA:
undetectable		 4p6xE-3glbA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A 271
GLY A 145
GLN A 131
LEU A 135
ILE A 302
 None
 1.37A 4p6xI-3glbA:
undetectable		 4p6xI-3glbA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 10 GLY A 251
ALA A 235
VAL A 252
ASP A 249
ILE A 250
 None
 1.17A 5i3cB-3glbA:
undetectable		 5i3cB-3glbA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 9 ILE A 109
PRO A 106
LEU A 159
ILE A 269
LEU A  92
 None
None
None
GOL  A   2 (-4.9A)
None
 1.48A 5iepA-3glbA:
undetectable		 5iepA-3glbA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 12 ILE A 109
LEU A  92
LEU A 101
ALA A 134
GLY A 138
 None
 1.04A 5uxdB-3glbA:
undetectable		 5uxdB-3glbA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		5 / 10 ILE A 207
LEU A 164
ALA A 247
LEU A 231
GLU A 125
 None
 0.95A 5y7pG-3glbA:
undetectable		 5y7pG-3glbA:
24.56