SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA502_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		6 / 9 HIS A  97
GLY A  15
GLU A  74
PHE A 126
GLN A  13
ILE A 144
 None
None
CIT  A 379 (-2.9A)
CIT  A 379 ( 4.8A)
CIT  A 379 (-2.8A)
None
 1.28A 1oltA-3gm5A:
0.0		 1oltA-3gm5A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		4 / 6 GLN A  26
PHE A  66
PRO A  37
LEU A  75
 None
 1.36A 3tgvD-3gm5A:
undetectable		 3tgvD-3gm5A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		4 / 8 TYR A 131
TYR A 133
HIS A  97
LEU A  63
 CIT  A 379 (-3.9A)
CIT  A 379 (-4.3A)
None
CIT  A 379 (-4.6A)
 1.06A 4jtrA-3gm5A:
undetectable		 4jtrA-3gm5A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		5 / 12 GLY A 124
GLN A 122
ALA A  48
ASN A  81
SER A  83
 None
 1.17A 4pd5A-3gm5A:
undetectable		 4pd5A-3gm5A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		3 / 3 GLU A  74
THR A  84
HIS A  97
 CIT  A 379 (-2.9A)
None
None
 0.57A 4q15A-3gm5A:
undetectable		 4q15A-3gm5A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		3 / 3 GLU A  74
THR A  84
HIS A  97
 CIT  A 379 (-2.9A)
None
None
 0.55A 4q15B-3gm5A:
undetectable		 4q15B-3gm5A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		3 / 3 MET A 118
GLN A 122
TYR A 131
 None
None
CIT  A 379 (-3.9A)
 1.09A 4udcA-3gm5A:
undetectable		 4udcA-3gm5A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		3 / 3 GLU A  74
THR A  84
HIS A  97
 CIT  A 379 (-2.9A)
None
None
 0.59A 4ydqB-3gm5A:
undetectable		 4ydqB-3gm5A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES
(Caldanaerobacter
subterraneus) 		5 / 12 THR A  50
SER A  83
THR A  84
ALA A  61
THR A  42
 None
None
None
None
CIT  A 379 (-4.0A)
 1.39A 5d0xH-3gm5A:
undetectable
5d0xI-3gm5A:
undetectable		 5d0xH-3gm5A:
18.50
5d0xI-3gm5A:
20.40