SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 ILE A 471
PRO A 492
THR A 494
LEU A 616
TYR A 617
 None
 1.11A 1cbsA-3gm8A:
undetectable		 1cbsA-3gm8A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 ALA A 608
LEU A 331
LEU A 332
LEU A 324
 None
 0.78A 1ereE-3gm8A:
undetectable		 1ereE-3gm8A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 ALA A 608
LEU A 331
LEU A 332
LEU A 324
 None
 0.78A 1ereF-3gm8A:
undetectable		 1ereF-3gm8A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 VAL A 320
ALA A 319
HIS A  57
 None
 0.78A 1q23C-3gm8A:
undetectable		 1q23C-3gm8A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 ALA A 375
TRP A  74
LEU A 156
GLY A  77
 None
 0.70A 1rukH-3gm8A:
5.2
1rukL-3gm8A:
6.0		 1rukH-3gm8A:
13.86
1rukL-3gm8A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 161
SER A 164
TYR A 109
HIS A 152
 None
 1.21A 2bteD-3gm8A:
undetectable		 2bteD-3gm8A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 SER A 255
ASP A 257
SER A 258
ASN A 298
 None
 0.99A 2cmlA-3gm8A:
undetectable		 2cmlA-3gm8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 SER A 255
ASP A 257
SER A 258
ASN A 298
 None
 0.97A 2cmlC-3gm8A:
undetectable		 2cmlC-3gm8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 SER A 255
ASP A 257
SER A 258
ASN A 298
 None
 1.01A 2cmlD-3gm8A:
undetectable		 2cmlD-3gm8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 GLU A 490
ILE A 462
LEU A 459
GLY A 441
ARG A 159
 GOL  A   1 (-2.5A)
None
None
None
GOL  A   1 (-3.0A)
 1.25A 2e7fA-3gm8A:
6.6		 2e7fA-3gm8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 GLU A 490
ILE A 462
LEU A 459
GLY A 441
ARG A 159
 GOL  A   1 (-2.5A)
None
None
None
GOL  A   1 (-3.0A)
 1.25A 2e7fB-3gm8A:
5.8		 2e7fB-3gm8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 ASN A 126
TYR A 167
SER A 130
 None
 0.90A 2gvcB-3gm8A:
undetectable		 2gvcB-3gm8A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 ASN A 126
TYR A 167
SER A 130
 None
 0.90A 2gvcE-3gm8A:
undetectable		 2gvcE-3gm8A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 GLU A 490
ILE A 462
LEU A 459
GLY A 441
ARG A 159
 GOL  A   1 (-2.5A)
None
None
None
GOL  A   1 (-3.0A)
 1.26A 2ogyA-3gm8A:
9.1		 2ogyA-3gm8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 GLU A 490
ILE A 462
LEU A 459
GLY A 441
ARG A 159
 GOL  A   1 (-2.5A)
None
None
None
GOL  A   1 (-3.0A)
 1.24A 2ogyB-3gm8A:
4.2		 2ogyB-3gm8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 ILE A 103
LEU A 172
LEU A 121
ASP A 134
 None
 1.01A 2rlfA-3gm8A:
undetectable
2rlfD-3gm8A:
undetectable		 2rlfA-3gm8A:
4.77
2rlfD-3gm8A:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 188
ARG A 399
PRO A 433
 None
 1.04A 2wljA-3gm8A:
4.1		 2wljA-3gm8A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 5 LEU A 577
PHE A 581
TRP A 621
TRP A 568
 None
 0.95A 2x2iC-3gm8A:
8.4		 2x2iC-3gm8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 ILE A 674
TYR A 648
VAL A 645
TYR A 555
 None
 1.20A 2xz5A-3gm8A:
undetectable
2xz5C-3gm8A:
2.6		 2xz5A-3gm8A:
15.37
2xz5C-3gm8A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 ILE A 674
TYR A 648
VAL A 645
TYR A 555
 None
 1.18A 2xz5C-3gm8A:
2.6
2xz5D-3gm8A:
undetectable		 2xz5C-3gm8A:
15.37
2xz5D-3gm8A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 674
TYR A 648
VAL A 645
TYR A 555
 None
 1.21A 2xz5D-3gm8A:
undetectable
2xz5E-3gm8A:
undetectable		 2xz5D-3gm8A:
15.37
2xz5E-3gm8A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 TYR A 742
GLU A 545
THR A 497
 None
 0.96A 2y7hB-3gm8A:
undetectable		 2y7hB-3gm8A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 135
TRP A 115
TYR A 133
 None
 1.02A 3aicA-3gm8A:
5.1		 3aicA-3gm8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 135
TRP A 115
TYR A 133
 None
 1.00A 3aicB-3gm8A:
2.9		 3aicB-3gm8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 135
TRP A 115
TYR A 133
 None
 1.01A 3aicE-3gm8A:
3.2		 3aicE-3gm8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 135
TRP A 115
TYR A 133
 None
 0.99A 3aicH-3gm8A:
3.5		 3aicH-3gm8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 GLN A 618
PHE A 615
TYR A 614
 None
 0.87A 3ucjB-3gm8A:
undetectable		 3ucjB-3gm8A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 GLN A 618
PHE A 615
TYR A 614
 None
 0.94A 3ucjA-3gm8A:
undetectable		 3ucjA-3gm8A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 5 ARG A 328
LEU A 325
VAL A 320
ASP A 309
 None
 1.03A 3ufnA-3gm8A:
undetectable
3ufnB-3gm8A:
undetectable		 3ufnA-3gm8A:
8.64
3ufnB-3gm8A:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 GLU A 490
ILE A 462
LEU A 459
GLY A 441
ARG A 159
 GOL  A   1 (-2.5A)
None
None
None
GOL  A   1 (-3.0A)
 1.33A 4djfB-3gm8A:
9.3		 4djfB-3gm8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.98A 4k8cA-3gm8A:
2.9		 4k8cA-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.95A 4kahA-3gm8A:
3.3		 4kahA-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.96A 4kahB-3gm8A:
3.0		 4kahB-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.97A 4kanA-3gm8A:
2.9		 4kanA-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.96A 4kbeB-3gm8A:
3.2		 4kbeB-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 SER A 713
ASN A 714
GLN A 788
LEU A 755
ILE A 812
 None
 1.28A 4kukA-3gm8A:
undetectable		 4kukA-3gm8A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 SER A 130
TYR A 182
PRO A 346
 None
 0.97A 4lbgB-3gm8A:
2.0		 4lbgB-3gm8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 LEU A 253
ARG A 285
MET A 406
 None
 0.89A 4m11C-3gm8A:
undetectable		 4m11C-3gm8A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 HIS A 311
TYR A 167
ASN A 364
ARG A 168
 None
 1.33A 4o7gA-3gm8A:
undetectable
4o7gB-3gm8A:
undetectable		 4o7gA-3gm8A:
15.59
4o7gB-3gm8A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 PHE A 284
VAL A 282
GLY A 283
LEU A 264
SER A 230
 None
 1.32A 4ot2A-3gm8A:
undetectable		 4ot2A-3gm8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 HIS A 152
ALA A  81
SER A  60
GLY A 158
GLY A 127
 None
 1.07A 4uilH-3gm8A:
6.5
4uilL-3gm8A:
5.6		 4uilH-3gm8A:
14.14
4uilL-3gm8A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 399
ASP A 398
ARG A 397
 None
 0.66A 4wq4B-3gm8A:
undetectable		 4wq4B-3gm8A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 5 TYR A 161
GLY A  63
TYR A 771
GLY A 759
 None
 0.99A 5ayfA-3gm8A:
undetectable		 5ayfA-3gm8A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 ALA A 339
ILE A 340
LYS A 333
LEU A 332
ALA A 613
 None
 1.15A 5bw4B-3gm8A:
undetectable		 5bw4B-3gm8A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 HIS A 152
VAL A 150
TYR A  86
HIS A  57
 None
 1.20A 5kkzA-3gm8A:
undetectable
5kkzG-3gm8A:
undetectable		 5kkzA-3gm8A:
18.87
5kkzG-3gm8A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 HIS A  57
HIS A 152
VAL A 150
TYR A  86
 None
 1.19A 5kkzC-3gm8A:
undetectable
5kkzE-3gm8A:
undetectable		 5kkzC-3gm8A:
13.11
5kkzE-3gm8A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 HIS A 152
VAL A 150
TYR A  86
HIS A  57
 None
 1.18A 5kkzK-3gm8A:
undetectable
5kkzQ-3gm8A:
undetectable		 5kkzK-3gm8A:
18.87
5kkzQ-3gm8A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 7 HIS A  57
HIS A 152
VAL A 150
TYR A  86
 None
 1.19A 5kkzM-3gm8A:
undetectable
5kkzO-3gm8A:
undetectable		 5kkzM-3gm8A:
13.11
5kkzO-3gm8A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 ILE A 604
HIS A 344
PHE A 586
GLY A 584
GLY A 602
 None
GOL  A   1 (-4.1A)
None
None
None
 1.17A 5l6eA-3gm8A:
undetectable		 5l6eA-3gm8A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 TRP A 160
HIS A 311
LEU A 110
SER A  60
 None
 1.35A 5syjA-3gm8A:
undetectable		 5syjA-3gm8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 TRP A 160
HIS A 311
LEU A 110
SER A  60
 None
 1.37A 5syjB-3gm8A:
undetectable		 5syjB-3gm8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 10 PRO A 631
HIS A 632
ALA A 613
GLY A 602
ILE A 603
 None
 0.98A 5vyhA-3gm8A:
undetectable		 5vyhA-3gm8A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 HIS A 152
PHE A  31
HIS A 311
THR A 312
 None
 1.00A 5yj1G-3gm8A:
undetectable
5yj1Y-3gm8A:
undetectable		 5yj1G-3gm8A:
8.78
5yj1Y-3gm8A:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 8 HIS A 311
THR A 312
HIS A 152
PHE A  31
 None
 1.07A 5yj1k-3gm8A:
undetectable
5yj1t-3gm8A:
undetectable		 5yj1k-3gm8A:
8.78
5yj1t-3gm8A:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		5 / 12 PHE A 284
VAL A 282
GLY A 283
LEU A 264
SER A 230
 None
 1.19A 6ci6A-3gm8A:
undetectable		 6ci6A-3gm8A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 GLY A 410
VAL A 362
PHE A 347
PHE A 351
 None
 0.81A 6h7lA-3gm8A:
undetectable		 6h7lA-3gm8A:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE
(Bacteroides
vulgatus) 		4 / 6 GLY A 410
VAL A 362
PHE A 347
PHE A 351
 None
 0.81A 6h7lB-3gm8A:
undetectable		 6h7lB-3gm8A:
8.75