SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		3 / 3 ILE A 111
PHE A 170
HIS A 124
 None
 0.75A 3h0aA-3gmfA:
undetectable		 3h0aA-3gmfA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		5 / 12 LEU A 237
SER A  78
ILE A  94
GLY A  52
ALA A  93
 None
 1.06A 3kk6A-3gmfA:
undetectable		 3kk6A-3gmfA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		4 / 7 ARG A 157
MET A 106
THR A 107
LEU A 110
 None
 0.92A 5b1aA-3gmfA:
undetectable
5b1aJ-3gmfA:
undetectable		 5b1aA-3gmfA:
16.83
5b1aJ-3gmfA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		3 / 3 ILE A 111
ILE A 161
MET A 171
 None
 0.70A 5i9yA-3gmfA:
undetectable		 5i9yA-3gmfA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		4 / 7 ARG A 157
MET A 106
THR A 107
LEU A 110
 None
 0.89A 5zcpA-3gmfA:
undetectable
5zcpJ-3gmfA:
undetectable		 5zcpA-3gmfA:
16.83
5zcpJ-3gmfA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gmf PROTEIN-DISULFIDE
ISOMERASE
(Novosphingobium
aromaticivorans) 		4 / 5 ARG A 157
MET A 106
THR A 107
LEU A 110
 None
 0.95A 6nknW-3gmfA:
undetectable		 6nknW-3gmfA:
12.62