SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 213
VAL A 212
GLY A 211
ASP A 226
 None
 1.44A 3w9tA-3gmgA:
undetectable		 3w9tA-3gmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 213
VAL A 212
GLY A 211
ASP A 226
 None
 1.43A 3w9tB-3gmgA:
undetectable		 3w9tB-3gmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 213
VAL A 212
GLY A 211
ASP A 226
 None
 1.44A 3w9tF-3gmgA:
undetectable		 3w9tF-3gmgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 202
MET A 184
MET A 249
LEU A 191
 None
 1.02A 4ok1A-3gmgA:
undetectable		 4ok1A-3gmgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 212
VAL A 158
GLY A 159
ARG A 280
 None
 0.98A 5d4nA-3gmgA:
4.4
5d4nC-3gmgA:
4.5		 5d4nA-3gmgA:
21.71
5d4nC-3gmgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 6 ARG A 261
ASP A 186
GLY A 254
ASP A 257
 None
 1.31A 5hp1A-3gmgA:
2.1		 5hp1A-3gmgA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 162
ARG A 273
VAL A 276
ASP A 275
 None
 1.02A 5vlmA-3gmgA:
undetectable		 5vlmA-3gmgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873
(Mycobacterium
tuberculosis) 		4 / 4 VAL A 259
GLY A 264
ASP A 174
ASP A 173
 None
 1.39A 6cjkC-3gmgA:
undetectable		 6cjkC-3gmgA:
22.17