SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	3gmt	ADENYLATE KINASE (Burkholderia pseudomallei)	5 / 11	TYR A 171 GLN A 174 PRO A 177 ILE A 116 ILE A 109	None	1.41A	3ganA-3gmtA: undetectable	3ganA-3gmtA: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	3gmt	ADENYLATE KINASE (Burkholderia pseudomallei)	4 / 6	LYS A 176 PRO A 177 LEU A 6 GLU A 108	None	1.35A	4z4cA-3gmtA: 2.3	4z4cA-3gmtA: 13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F1A_A_SALA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3gmt	ADENYLATE KINASE (Burkholderia pseudomallei)	5 / 8	VAL A 68 LEU A 72 LEU A 194 GLY A 100 ALA A 99	None	1.24A	5f1aA-3gmtA: undetectable	5f1aA-3gmtA: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J2T_C_VLBC503_1 (TUBULIN BETA-2B CHAIN TUBULIN ALPHA-1B CHAIN)	3gmt	ADENYLATE KINASE (Burkholderia pseudomallei)	5 / 9	VAL A 106 ASP A 104 TYR A 182 PRO A 87 LEU A 6	None	1.27A	5j2tB-3gmtA: 1.9	5j2tB-3gmtA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUK_A_Z80A201_1 (BETA-LACTOGLOBULIN)	3gmt	ADENYLATE KINASE (Burkholderia pseudomallei)	5 / 10	PHE A 83 ILE A 4 ILE A 103 VAL A 101 ALA A 95	None	1.15A	5nukA-3gmtA: undetectable	5nukA-3gmtA: 20.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","3gmt","ADENYLATE KINASE","Burkholderia pseudomallei",5,"TYR A 171;GLN A 174;PRO A 177;ILE A 116;ILE A 109","None","1.41A","3ganA-3gmtA:undetectable","3ganA-3gmtA:21.03"],["4Z4C_A_IPHA904_0","PROTEIN ARGONAUTE-2","3gmt","ADENYLATE KINASE","Burkholderia pseudomallei",4,"LYS A 176;PRO A 177;LEU A   6;GLU A 108","None","1.35A","4z4cA-3gmtA:2.3","4z4cA-3gmtA:13.90"],["5F1A_A_SALA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3gmt","ADENYLATE KINASE","Burkholderia pseudomallei",5,"VAL A  68;LEU A  72;LEU A 194;GLY A 100;ALA A  99","None","1.24A","5f1aA-3gmtA:undetectable","5f1aA-3gmtA:17.89"],["5J2T_C_VLBC503_1","TUBULIN BETA-2B CHAIN;TUBULIN ALPHA-1B CHAIN","3gmt","ADENYLATE KINASE","Burkholderia pseudomallei",5,"VAL A 106;ASP A 104;TYR A 182;PRO A  87;LEU A   6","None","1.27A","5j2tB-3gmtA:1.9","5j2tB-3gmtA:21.25"],["5NUK_A_Z80A201_1","BETA-LACTOGLOBULIN","3gmt","ADENYLATE KINASE","Burkholderia pseudomallei",5,"PHE A  83;ILE A   4;ILE A 103;VAL A 101;ALA A  95","None","1.15A","5nukA-3gmtA:undetectable","5nukA-3gmtA:20.49"]]