SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		3 / 3 ASP A  26
LEU A  29
HIS A 141
 None
 0.79A 1qknA-3gn6A:
undetectable		 1qknA-3gn6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		3 / 3 LEU A  69
PRO A  70
ARG A 128
 None
 0.59A 2qd4B-3gn6A:
undetectable		 2qd4B-3gn6A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		3 / 3 TYR A 249
MET A 272
LEU A 221
 None
 0.92A 3vw1D-3gn6A:
undetectable		 3vw1D-3gn6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		5 / 12 GLU A 191
LEU A 258
VAL A 168
ILE A 257
LEU A 221
 None
 1.41A 4k36A-3gn6A:
undetectable		 4k36A-3gn6A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		5 / 12 GLU A 191
LEU A 258
VAL A 168
ILE A 257
LEU A 221
 None
 1.42A 4k36B-3gn6A:
undetectable		 4k36B-3gn6A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		5 / 11 GLU A 191
LEU A 258
VAL A 168
ILE A 257
LEU A 221
 None
 1.45A 4k37A-3gn6A:
undetectable		 4k37A-3gn6A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		5 / 12 GLU A 191
LEU A 258
VAL A 168
ILE A 257
LEU A 221
 None
 1.44A 4k38B-3gn6A:
undetectable		 4k38B-3gn6A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		4 / 7 TYR A  42
GLU A 256
GLU A 201
GLU A 191
 None
 1.14A 4mi4A-3gn6A:
undetectable
4mi4C-3gn6A:
undetectable		 4mi4A-3gn6A:
20.81
4mi4C-3gn6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		4 / 6 LEU A 222
HIS A 286
HIS A 282
GLU A 308
 None
MG  A 321 ( 3.3A)
MG  A 321 (-3.3A)
MG  A 321 (-1.8A)
 1.05A 4pahA-3gn6A:
undetectable		 4pahA-3gn6A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		3 / 3 LYS A 153
ARG A  46
VAL A  47
 None
GOL  A 324 (-3.6A)
None
 0.85A 4x3uA-3gn6A:
undetectable
4x3uB-3gn6A:
undetectable		 4x3uA-3gn6A:
10.94
4x3uB-3gn6A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		4 / 7 ARG A 259
VAL A 218
TRP A 214
HIS A 211
 None
 1.36A 5ad9A-3gn6A:
undetectable
5ad9B-3gn6A:
undetectable		 5ad9A-3gn6A:
20.63
5ad9B-3gn6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		5 / 12 LEU A  77
PHE A 132
PHE A 136
ALA A 159
LEU A 144
 None
 1.21A 5iepA-3gn6A:
undetectable		 5iepA-3gn6A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 3gn6 CT0912, ORFAN
PROTEIN WITH A
FERREDOXIN-LIKE
DOMAIN REPEAT
(Chlorobaculum
tepidum) 		4 / 7 VAL A 218
ARG A 259
TYR A 270
GLU A 215
 None
 0.97A 5umwB-3gn6A:
undetectable
5umwE-3gn6A:
undetectable		 5umwB-3gn6A:
12.46
5umwE-3gn6A:
12.46