SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_A_5FWA601_1 (BETA-1 ADRENERGIC RECEPTOR)	3gnm	JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN (Mus musculus)	5 / 12	VAL H 168 VAL H 186 SER H 184 ASN H 201 ASN H 160	None	1.43A	2y03A-3gnmH: undetectable	2y03A-3gnmH: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_B_5FWB601_1 (BETA-1 ADRENERGIC RECEPTOR)	3gnm	JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN (Mus musculus)	5 / 12	VAL H 168 VAL H 186 SER H 184 ASN H 201 ASN H 160	None	1.47A	2y03B-3gnmH: undetectable	2y03B-3gnmH: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	3gnm	JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN (Mus musculus)	5 / 12	VAL H 168 VAL H 186 SER H 184 ASN H 201 ASN H 160	None	1.43A	3nyaA-3gnmH: undetectable	3nyaA-3gnmH: 18.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MTH_A_ACTA302_0 (ANTIBODY FAB HEAVY CHAIN)	3gnm	JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN (Mus musculus)	4 / 5	SER H 117 ALA H 119 PHE H 151 LEU H 175	None	0.35A	5mthA-3gnmH: 30.0	5mthA-3gnmH: 69.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7M_B_68HB405_0 (BETA-1 ADRENERGIC RECEPTOR)	3gnm	JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN (Mus musculus)	5 / 12	VAL H 168 VAL H 186 SER H 184 ASN H 201 ASN H 160	None	1.46A	6h7mB-3gnmH: undetectable	6h7mB-3gnmH: 18.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y03_A_5FWA601_1","BETA-1 ADRENERGIC RECEPTOR","3gnm","JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN","Mus musculus",5,"VAL H 168;VAL H 186;SER H 184;ASN H 201;ASN H 160","None","1.43A","2y03A-3gnmH:undetectable","2y03A-3gnmH:19.87"],["2Y03_B_5FWB601_1","BETA-1 ADRENERGIC RECEPTOR","3gnm","JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN","Mus musculus",5,"VAL H 168;VAL H 186;SER H 184;ASN H 201;ASN H 160","None","1.47A","2y03B-3gnmH:undetectable","2y03B-3gnmH:19.87"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","3gnm","JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN","Mus musculus",5,"VAL H 168;VAL H 186;SER H 184;ASN H 201;ASN H 160","None","1.43A","3nyaA-3gnmH:undetectable","3nyaA-3gnmH:18.36"],["5MTH_A_ACTA302_0","ANTIBODY FAB HEAVY CHAIN","3gnm","JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN","Mus musculus",4,"SER H 117;ALA H 119;PHE H 151;LEU H 175","None","0.35A","5mthA-3gnmH:30.0","5mthA-3gnmH:69.68"],["6H7M_B_68HB405_0","BETA-1 ADRENERGIC RECEPTOR","3gnm","JAA-F11 FAB ANTIBODY FRAGMENT, HEAVY CHAIN","Mus musculus",5,"VAL H 168;VAL H 186;SER H 184;ASN H 201;ASN H 160","None","1.46A","6h7mB-3gnmH:undetectable","6h7mB-3gnmH:18.02"]]