SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_A_DVAA6_0 (GRAMICIDIN D)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	3 / 3	ALA P 69 VAL P 71 TRP P 88	None	0.98A	2izqA-3gnuP: undetectable 2izqB-3gnuP: undetectable	2izqA-3gnuP: 6.82 2izqB-3gnuP: 6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_A_PZIA802_0 (GLUTAMATE RECEPTOR 2)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	3 / 3	ASP P 93 ASN P 194 SER P 153	None GAI P 214 (-3.3A) None	0.68A	3lslA-3gnuP: undetectable 3lslD-3gnuP: undetectable	3lslA-3gnuP: 21.92 3lslD-3gnuP: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_D_PZID802_0 (GLUTAMATE RECEPTOR 2)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	3 / 3	SER P 153 ASP P 93 ASN P 194	None None GAI P 214 (-3.3A)	0.68A	3lslA-3gnuP: undetectable 3lslD-3gnuP: undetectable	3lslA-3gnuP: 21.92 3lslD-3gnuP: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_1 (RNA-DIRECTED RNA POLYMERASE L)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	3 / 3	SER P 126 ASP P 191 ASP P 104	None	0.80A	4uckA-3gnuP: undetectable	4uckA-3gnuP: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_DIFA602_1 (SERUM ALBUMIN)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	4 / 8	ASP P 18 ALA P 22 VAL P 25 GLU P 15	None	0.76A	4zbqA-3gnuP: undetectable	4zbqA-3gnuP: 14.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NNW_D_GCSD302_1 (25 KDA PROTEIN ELICITOR)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	5 / 7	ASP P 93 GLY P 100 ASP P 104 HIS P 128 ASP P 158	None None None GAI P 214 (-4.1A) GAI P 214 (-2.7A)	1.37A	5nnwD-3gnuP: 38.6	5nnwD-3gnuP: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NO9_D_95ZD302_1 (25 KDA PROTEIN ELICITOR)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	5 / 7	ASP P 93 GLY P 100 ASP P 104 HIS P 128 ASP P 158	None None None GAI P 214 (-4.1A) GAI P 214 (-2.7A)	1.38A	5no9D-3gnuP: 39.0	5no9D-3gnuP: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6J_D_ACTD404_0 (L-LYSINE 3-HYDROXYLASE)	3gnu	25 KDA PROTEIN ELICITOR (Pythium aphanidermatum)	4 / 6	GLN P 178 GLU P 15 ALA P 22 GLN P 21	None	1.14A	6f6jC-3gnuP: undetectable 6f6jD-3gnuP: undetectable	6f6jC-3gnuP: 19.72 6f6jD-3gnuP: 19.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2IZQ_A_DVAA6_0","GRAMICIDIN D","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",3,"ALA P  69;VAL P  71;TRP P  88","None","0.98A","2izqA-3gnuP:undetectable;2izqB-3gnuP:undetectable","2izqA-3gnuP:6.82;2izqB-3gnuP:6.82"],["3LSL_A_PZIA802_0","GLUTAMATE RECEPTOR 2","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",3,"ASP P  93;ASN P 194;SER P 153","None;GAI P 214 (-3.3A);None","0.68A","3lslA-3gnuP:undetectable;3lslD-3gnuP:undetectable","3lslA-3gnuP:21.92;3lslD-3gnuP:21.92"],["3LSL_D_PZID802_0","GLUTAMATE RECEPTOR 2","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",3,"SER P 153;ASP P  93;ASN P 194","None;None;GAI P 214 (-3.3A)","0.68A","3lslA-3gnuP:undetectable;3lslD-3gnuP:undetectable","3lslA-3gnuP:21.92;3lslD-3gnuP:21.92"],["4UCK_A_SAMA2409_1","RNA-DIRECTED RNA POLYMERASE L","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",3,"SER P 126;ASP P 191;ASP P 104","None","0.80A","4uckA-3gnuP:undetectable","4uckA-3gnuP:18.23"],["4ZBQ_A_DIFA602_1","SERUM ALBUMIN","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",4,"ASP P  18;ALA P  22;VAL P  25;GLU P  15","None","0.76A","4zbqA-3gnuP:undetectable","4zbqA-3gnuP:14.60"],["5NNW_D_GCSD302_1","25 KDA PROTEIN ELICITOR","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",5,"ASP P  93;GLY P 100;ASP P 104;HIS P 128;ASP P 158","None;None;None;GAI P 214 (-4.1A);GAI P 214 (-2.7A)","1.37A","5nnwD-3gnuP:38.6","5nnwD-3gnuP:100.00"],["5NO9_D_95ZD302_1","25 KDA PROTEIN ELICITOR","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",5,"ASP P  93;GLY P 100;ASP P 104;HIS P 128;ASP P 158","None;None;None;GAI P 214 (-4.1A);GAI P 214 (-2.7A)","1.38A","5no9D-3gnuP:39.0","5no9D-3gnuP:100.00"],["6F6J_D_ACTD404_0","L-LYSINE 3-HYDROXYLASE","3gnu","25 KDA PROTEIN ELICITOR","Pythium aphanidermatum",4,"GLN P 178;GLU P  15;ALA P  22;GLN P  21","None","1.14A","6f6jC-3gnuP:undetectable;6f6jD-3gnuP:undetectable","6f6jC-3gnuP:19.72;6f6jD-3gnuP:19.72"]]