SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3go5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		5 / 10 ALA A 252
LEU A 241
ILE A 228
LEU A 265
ILE A 256
 None
 1.12A 3jw3A-3go5A:
undetectable		 3jw3A-3go5A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		3 / 3 ARG A 203
PRO A 145
PHE A 202
 None
 0.97A 3thrC-3go5A:
undetectable		 3thrC-3go5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		4 / 4 THR A  51
ASP A  52
ARG A  58
LEU A  57
 None
 1.25A 5tdmA-3go5A:
undetectable		 5tdmA-3go5A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		4 / 5 ARG A 120
ALA A 134
TYR A 135
ILE A 102
 None
 0.98A 6f6sA-3go5A:
undetectable
6f6sB-3go5A:
undetectable		 6f6sA-3go5A:
15.56
6f6sB-3go5A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		4 / 5 ARG A 120
ALA A 134
TYR A 135
ILE A 102
 None
 1.03A 6g9bA-3go5A:
undetectable
6g9bB-3go5A:
undetectable		 6g9bA-3go5A:
15.56
6g9bB-3go5A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3go5 MULTIDOMAIN PROTEIN
WITH S1 RNA-BINDING
DOMAINS
(Streptococcus
pneumoniae) 		4 / 7 GLY A 166
THR A 167
PHE A 179
SER A 212
 None
 0.96A 6jnhA-3go5A:
undetectable		 6jnhA-3go5A:
21.28