SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3go7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.29A 1bx4A-3go7A:
27.3		 1bx4A-3go7A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  86
PHE A  69
VAL A  67
VAL A  18
 None
 0.71A 1epbA-3go7A:
undetectable		 1epbA-3go7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  86
PHE A  69
VAL A  67
VAL A  18
 None
 0.78A 1epbB-3go7A:
undetectable		 1epbB-3go7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.34A 1liiA-3go7A:
29.6		 1liiA-3go7A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.46A 1likA-3go7A:
29.5		 1likA-3go7A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		3 / 3 GLY A 257
GLU A 261
ASN A 255
 None
 0.68A 1zq9A-3go7A:
3.8		 1zq9A-3go7A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ALA A 106
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-3.3A)
RIB  A 305 (-2.9A)
 0.31A 2c49A-3go7A:
34.4		 2c49A-3go7A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 ASP A  25
GLY A  50
GLY A  51
ASN A  55
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
 0.51A 2c49B-3go7A:
31.2		 2c49B-3go7A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 THR A  27
ALA A  54
ASN A  55
LEU A  82
 None
None
RIB  A 305 (-3.2A)
None
 1.03A 2hzqA-3go7A:
undetectable		 2hzqA-3go7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		7 / 12 SER A  21
ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 ( 4.7A)
RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.55A 2pkkA-3go7A:
31.0		 2pkkA-3go7A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		7 / 12 SER A  21
ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 ( 4.7A)
RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.55A 2pkmA-3go7A:
30.9		 2pkmA-3go7A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 SER A 103
ALA A 124
GLY A 104
ASN A  23
ALA A  78
GLY A  50
 None
None
None
RIB  A 305 (-3.7A)
None
RIB  A 305 ( 3.7A)
 1.48A 2pkmA-3go7A:
30.9		 2pkmA-3go7A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 SER A 103
ALA A 124
GLY A 104
ASN A  23
ALA A  78
GLY A  51
 None
None
None
RIB  A 305 (-3.7A)
None
RIB  A 305 (-3.1A)
 1.38A 2pkmA-3go7A:
30.9		 2pkmA-3go7A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 216
GLY A 241
GLY A 212
ALA A 245
LEU A 142
 None
 1.07A 2plwA-3go7A:
3.8		 2plwA-3go7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 224
VAL A 219
GLY A 220
ARG A 217
 None
 0.97A 3bjwC-3go7A:
undetectable		 3bjwC-3go7A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 8 VAL A 224
VAL A 219
GLY A 220
ARG A 217
 None
 0.98A 3bjwA-3go7A:
undetectable		 3bjwA-3go7A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 286
GLY A 283
VAL A 282
GLY A 239
VAL A  58
 None
None
None
RIB  A 305 ( 4.5A)
None
 1.20A 3f8wC-3go7A:
undetectable		 3f8wC-3go7A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  82
PHE A  73
ALA A  72
ALA A 134
GLY A  92
 None
 0.98A 3nxuA-3go7A:
undetectable		 3nxuA-3go7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 ASN A 251
ALA A 250
ARG A  62
ALA A 272
 None
 1.14A 3twpA-3go7A:
7.0		 3twpA-3go7A:
27.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.42A 3uboA-3go7A:
30.6		 3uboA-3go7A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  50
GLY A  51
ASN A  55
GLU A 146
GLY A 239
 RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.6A)
RIB  A 305 ( 4.5A)
 0.83A 3uboA-3go7A:
30.6		 3uboA-3go7A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.34A 3uboB-3go7A:
31.7		 3uboB-3go7A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.38A 3uq6A-3go7A:
27.7		 3uq6A-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.36A 3uq6B-3go7A:
26.8		 3uq6B-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.44A 3vaqA-3go7A:
27.3		 3vaqA-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.42A 3vaqB-3go7A:
26.5		 3vaqB-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  51
ASN A  55
VAL A 120
GLY A 239
ASP A 242
 RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 1.03A 3vaqB-3go7A:
26.5		 3vaqB-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.39A 3vasA-3go7A:
27.5		 3vasA-3go7A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.33A 3vasB-3go7A:
18.7		 3vasB-3go7A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  51
ASN A  55
VAL A 120
GLY A 239
ASP A 242
 RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.99A 3vasB-3go7A:
18.7		 3vasB-3go7A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 6 GLU A 196
ASP A 242
ASN A 116
GLU A 115
 None
RIB  A 305 (-2.9A)
None
None
 1.20A 3vywA-3go7A:
2.7		 3vywA-3go7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 5 GLU A 196
ASP A 242
ASN A 116
GLU A 115
 None
RIB  A 305 (-2.9A)
None
None
 1.16A 3vywD-3go7A:
undetectable		 3vywD-3go7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 9 ASN A  55
GLY A  51
GLY A  50
GLY A  53
ASP A 242
 RIB  A 305 (-3.2A)
RIB  A 305 (-3.1A)
RIB  A 305 ( 3.7A)
None
RIB  A 305 (-2.9A)
 1.04A 3ztvA-3go7A:
undetectable		 3ztvA-3go7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.50A 4dc3A-3go7A:
26.1		 4dc3A-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.43A 4dc3B-3go7A:
27.4		 4dc3B-3go7A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.32A 4e3aA-3go7A:
31.6		 4e3aA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.39A 4e3aB-3go7A:
31.3		 4e3aB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  50
GLY A  51
ASN A  55
GLU A 146
GLY A 239
 RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.6A)
RIB  A 305 ( 4.5A)
 0.74A 4e3aB-3go7A:
31.3		 4e3aB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4jksA-3go7A:
31.8		 4jksA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4jksB-3go7A:
31.8		 4jksB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.46A 4jkuA-3go7A:
31.8		 4jkuA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.32A 4jkuB-3go7A:
31.8		 4jkuB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.50A 4k8cA-3go7A:
31.7		 4k8cA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.49A 4k8cB-3go7A:
31.6		 4k8cB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4k8kA-3go7A:
31.7		 4k8kA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.46A 4k8kB-3go7A:
31.7		 4k8kB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4k8pA-3go7A:
31.7		 4k8pA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4k8pB-3go7A:
31.7		 4k8pB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4k8tA-3go7A:
31.6		 4k8tA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.34A 4k8tB-3go7A:
31.7		 4k8tB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.32A 4k93A-3go7A:
31.8		 4k93A-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4k93B-3go7A:
31.8		 4k93B-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.32A 4k9cA-3go7A:
31.8		 4k9cA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4k9cB-3go7A:
31.8		 4k9cB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.33A 4k9iA-3go7A:
31.8		 4k9iA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.33A 4k9iB-3go7A:
31.8		 4k9iB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.31A 4kadA-3go7A:
31.8		 4kadA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.33A 4kadB-3go7A:
31.7		 4kadB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4kahA-3go7A:
31.8		 4kahA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.49A 4kahB-3go7A:
31.7		 4kahB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.45A 4kalA-3go7A:
31.8		 4kalA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4kalB-3go7A:
31.8		 4kalB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4kanA-3go7A:
31.8		 4kanA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.48A 4kanB-3go7A:
31.7		 4kanB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.48A 4kbeA-3go7A:
31.8		 4kbeA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.48A 4kbeB-3go7A:
27.4		 4kbeB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.47A 4lbgA-3go7A:
31.6		 4lbgA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.48A 4lbgB-3go7A:
31.7		 4lbgB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.34A 4lbxA-3go7A:
31.7		 4lbxA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.34A 4lbxB-3go7A:
31.8		 4lbxB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.33A 4lc4A-3go7A:
31.6		 4lc4A-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.33A 4lc4B-3go7A:
31.6		 4lc4B-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.49A 4lcaA-3go7A:
31.8		 4lcaA-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
ILE A 108
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
None
RIB  A 305 (-2.9A)
 0.48A 4lcaB-3go7A:
31.7		 4lcaB-3go7A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 ASP A  25
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.45A 4n09A-3go7A:
28.9		 4n09A-3go7A:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.52A 4n09B-3go7A:
28.7		 4n09B-3go7A:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.51A 4n09C-3go7A:
28.9		 4n09C-3go7A:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.54A 4n09D-3go7A:
28.7		 4n09D-3go7A:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		3 / 3 SER A  21
ALA A  72
VAL A  97
 RIB  A 305 ( 4.7A)
None
None
 0.60A 4o2bC-3go7A:
4.2		 4o2bC-3go7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 152
ALA A 155
ALA A 156
ALA A 159
 None
 0.09A 4oadA-3go7A:
undetectable		 4oadA-3go7A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 152
ALA A 155
ALA A 156
ALA A 159
 None
 0.09A 4oaeA-3go7A:
undetectable		 4oaeA-3go7A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 SER A  21
ASP A  25
GLY A  50
GLY A  51
ASN A  55
ASP A 242
 RIB  A 305 ( 4.7A)
RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.9A)
 0.52A 4ubeA-3go7A:
31.0		 4ubeA-3go7A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 241
ALA A 240
PRO A 230
THR A 277
VAL A 232
 None
 0.88A 4xdrA-3go7A:
undetectable		 4xdrA-3go7A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 241
GLY A 239
THR A 277
ASP A 242
ILE A 191
 None
RIB  A 305 ( 4.5A)
None
RIB  A 305 (-2.9A)
None
 0.82A 5bw4A-3go7A:
undetectable		 5bw4A-3go7A:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		6 / 12 ASP A  25
GLY A  50
GLY A  51
ASN A  55
GLY A 239
ASP A 242
 RIB  A 305 (-2.8A)
RIB  A 305 ( 3.7A)
RIB  A 305 (-3.1A)
RIB  A 305 (-3.2A)
RIB  A 305 ( 4.5A)
RIB  A 305 (-2.9A)
 0.33A 5kb5A-3go7A:
29.8		 5kb5A-3go7A:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 216
THR A 210
ALA A 274
GLY A 273
ALA A 269
 None
 1.09A 5lf3H-3go7A:
undetectable
5lf3I-3go7A:
undetectable		 5lf3H-3go7A:
20.43
5lf3I-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 216
THR A 210
ALA A 274
GLY A 273
ALA A 269
 None
 1.09A 5lf3V-3go7A:
undetectable
5lf3W-3go7A:
undetectable		 5lf3V-3go7A:
20.43
5lf3W-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 216
ALA A 274
GLY A 273
ALA A 269
LEU A 142
 None
 1.00A 5lf7H-3go7A:
undetectable
5lf7I-3go7A:
undetectable		 5lf7H-3go7A:
20.43
5lf7I-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 216
THR A 210
ALA A 274
GLY A 273
ALA A 269
 None
 1.09A 5lf7H-3go7A:
undetectable
5lf7I-3go7A:
undetectable		 5lf7H-3go7A:
20.43
5lf7I-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 216
ALA A 274
GLY A 273
ALA A 269
LEU A 142
 None
 0.98A 5lf7V-3go7A:
undetectable
5lf7W-3go7A:
undetectable		 5lf7V-3go7A:
20.43
5lf7W-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 216
THR A 210
ALA A 274
GLY A 273
ALA A 269
 None
 1.07A 5lf7V-3go7A:
undetectable
5lf7W-3go7A:
undetectable		 5lf7V-3go7A:
20.43
5lf7W-3go7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  53
GLU A 146
GLY A  20
VAL A 168
ALA A 245
 None
RIB  A 305 (-2.6A)
None
None
None
 0.86A 5o96G-3go7A:
3.3		 5o96G-3go7A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 5 ASN A 169
ASP A 242
ASN A  55
ASP A  25
 None
RIB  A 305 (-2.9A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.8A)
 1.05A 5vooA-3go7A:
2.2		 5vooA-3go7A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 5 ASN A 169
ASP A 242
ASN A  55
ASP A  25
 None
RIB  A 305 (-2.9A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.8A)
 1.06A 5vooC-3go7A:
undetectable		 5vooC-3go7A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 5 ASN A 169
ASP A 242
ASN A  55
ASP A  25
 None
RIB  A 305 (-2.9A)
RIB  A 305 (-3.2A)
RIB  A 305 (-2.8A)
 1.08A 5vooE-3go7A:
2.2		 5vooE-3go7A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  50
THR A  46
THR A  27
ARG A  62
GLY A 239
 RIB  A 305 ( 3.7A)
None
None
None
RIB  A 305 ( 4.5A)
 1.25A 5w97A-3go7A:
undetectable
5w97B-3go7A:
undetectable
5w97g-3go7A:
undetectable		 5w97A-3go7A:
19.54
5w97B-3go7A:
18.75
5w97g-3go7A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		3 / 3 SER A  21
ALA A  72
VAL A  97
 RIB  A 305 ( 4.7A)
None
None
 0.53A 5xiwC-3go7A:
4.8		 5xiwC-3go7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 276
THR A 277
GLN A  56
VAL A 243
 None
 0.93A 6cduA-3go7A:
undetectable
6cduE-3go7A:
undetectable		 6cduA-3go7A:
21.45
6cduE-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 6 GLN A  56
VAL A 243
ALA A 276
THR A 277
 None
 0.96A 6cduB-3go7A:
undetectable
6cduC-3go7A:
undetectable		 6cduB-3go7A:
21.45
6cduC-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 GLN A  56
VAL A 243
ALA A 276
THR A 277
 None
 0.90A 6cduC-3go7A:
undetectable
6cduD-3go7A:
undetectable		 6cduC-3go7A:
21.45
6cduD-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 8 GLN A  56
VAL A 243
ALA A 276
THR A 277
 None
 0.89A 6cduD-3go7A:
undetectable
6cduE-3go7A:
undetectable		 6cduD-3go7A:
21.45
6cduE-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 276
THR A 277
GLN A  56
VAL A 243
 None
 0.86A 6cduF-3go7A:
undetectable
6cduJ-3go7A:
undetectable		 6cduF-3go7A:
21.45
6cduJ-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 7 GLN A  56
VAL A 243
ALA A 276
THR A 277
 None
 0.93A 6cduH-3go7A:
undetectable
6cduI-3go7A:
undetectable		 6cduH-3go7A:
21.45
6cduI-3go7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 223
GLY A 220
HIS A 206
VAL A 189
GLU A 226
 None
 1.45A 6gnfA-3go7A:
7.0		 6gnfA-3go7A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 4 ALA A  60
ALA A  63
ALA A 250
ALA A 249
 None
 0.84A 6gtqA-3go7A:
undetectable
6gtqB-3go7A:
undetectable		 6gtqA-3go7A:
21.26
6gtqB-3go7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3go7 RIBOKINASE RBSK
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 250
ALA A 249
ALA A  60
ALA A  63
 None
 0.83A 6gtqA-3go7A:
undetectable
6gtqB-3go7A:
undetectable		 6gtqA-3go7A:
21.26
6gtqB-3go7A:
21.26