SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3goa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.07A 1a52A-3goaA:
undetectable		 1a52A-3goaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.07A 1a52B-3goaA:
undetectable		 1a52B-3goaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 ALA A 265
ARG A 264
GLU A 188
ILE A  10
LEU A  38
 None
CL  A 388 (-2.8A)
None
None
None
 1.23A 1d1gA-3goaA:
undetectable		 1d1gA-3goaA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 GLU A 188
ILE A 357
ILE A   6
ALA A 247
GLU A 361
 None
 1.44A 1ki7A-3goaA:
undetectable		 1ki7A-3goaA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 GLU A 188
ILE A 357
ILE A   6
ALA A 247
GLU A 361
 None
 1.32A 1ki7B-3goaA:
undetectable		 1ki7B-3goaA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 11 LEU A 341
GLY A 244
GLY A  15
ILE A 189
LEU A 359
 None
 1.13A 1p91A-3goaA:
undetectable		 1p91A-3goaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.09A 1pcgA-3goaA:
undetectable		 1pcgA-3goaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 GLY A 122
VAL A 124
MET A 126
SER A  17
ASP A 243
 None
 1.15A 1pk7C-3goaA:
undetectable		 1pk7C-3goaA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 11 GLY A 122
VAL A 124
MET A 126
SER A  17
ASP A 243
 None
 1.12A 1pk9C-3goaA:
undetectable		 1pk9C-3goaA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.11A 1qkuA-3goaA:
undetectable		 1qkuA-3goaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.11A 1qkuB-3goaA:
undetectable		 1qkuB-3goaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.10A 1qkuC-3goaA:
undetectable		 1qkuC-3goaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 SER A  37
ILE A  10
ALA A 247
ALA A  72
 None
 0.97A 1w0gA-3goaA:
undetectable		 1w0gA-3goaA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		3 / 3 GLY A  15
GLU A 208
ASP A 243
 None
 0.59A 2b25B-3goaA:
undetectable		 2b25B-3goaA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 ILE A 160
PRO A 284
SER A 288
MET A 307
 None
 1.37A 2qd3B-3goaA:
undetectable		 2qd3B-3goaA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 4 SER A  17
GLY A 122
GLY A  15
GLY A 244
 None
 0.76A 3bogB-3goaA:
undetectable
3bogD-3goaA:
undetectable		 3bogB-3goaA:
undetectable
3bogD-3goaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.07A 3q95A-3goaA:
undetectable		 3q95A-3goaA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 7 PRO A 277
MET A 280
GLY A 283
PRO A 284
 None
 1.26A 3ucbB-3goaA:
undetectable		 3ucbB-3goaA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 GLY A  65
ILE A  68
GLN A  60
VAL A 124
 None
 1.04A 4d39B-3goaA:
undetectable		 4d39B-3goaA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 8 GLY A 122
GLU A  63
VAL A 118
GLU A 119
 None
 0.75A 4fgzA-3goaA:
undetectable		 4fgzA-3goaA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 GLY A  65
ILE A  68
GLN A  60
VAL A 124
 None
 1.03A 4kcnA-3goaA:
undetectable		 4kcnA-3goaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 ASN A  71
THR A  86
ALA A  84
VAL A  82
ILE A  53
 None
 0.98A 4x1kD-3goaA:
undetectable		 4x1kD-3goaA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 11 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.11A 5dxbB-3goaA:
undetectable		 5dxbB-3goaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 PHE A 367
SER A 269
ALA A 295
LEU A 369
 None
 1.04A 5dzkB-3goaA:
undetectable
5dzkP-3goaA:
undetectable		 5dzkB-3goaA:
20.89
5dzkP-3goaA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 7 PHE A 367
SER A 269
ALA A 295
LEU A 369
 None
 1.08A 5dzkD-3goaA:
undetectable
5dzkR-3goaA:
undetectable		 5dzkD-3goaA:
20.89
5dzkR-3goaA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 6 PHE A 367
SER A 269
ALA A 295
LEU A 369
 None
 1.02A 5dzkg-3goaA:
undetectable
5dzku-3goaA:
undetectable		 5dzkg-3goaA:
20.89
5dzku-3goaA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 ALA A 246
LEU A  34
MET A  35
LEU A  38
ILE A  53
 None
 1.12A 5gtrA-3goaA:
undetectable		 5gtrA-3goaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 12 ILE A 352
PRO A 344
GLU A 309
GLY A 337
HIS A 173
 None
 1.15A 5l6eA-3goaA:
undetectable		 5l6eA-3goaA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		4 / 8 ARG A 362
GLU A 188
THR A 180
ILE A 210
 None
 1.01A 6a4iA-3goaA:
undetectable		 6a4iA-3goaA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 ASN A 335
ASP A 207
ASN A 358
GLU A 188
ARG A  11
 None
None
CL  A 388 (-3.2A)
None
None
 1.38A 6b94A-3goaA:
undetectable
6b94B-3goaA:
undetectable		 6b94A-3goaA:
10.25
6b94B-3goaA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		5 / 10 SER A 348
ASN A 308
HIS A 343
GLU A 306
GLU A 188
 None
 1.40A 6cggB-3goaA:
0.0		 6cggB-3goaA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 3goa 3-KETOACYL-COA
THIOLASE
(Salmonella
enterica) 		3 / 3 ARG A  23
PHE A  22
GLY A  20
 None
 0.77A 6fgdA-3goaA:
undetectable		 6fgdA-3goaA:
21.52