SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3god'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 228
LEU A 300
LEU A 236
LEU A  80
 None
 1.23A 1a4lD-3godA:
undetectable		 1a4lD-3godA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 135
VAL A 252
LEU A 262
LEU A 313
THR A 312
 None
 1.18A 1dmyA-3godA:
undetectable		 1dmyA-3godA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 180
LEU A 177
ARG A 138
LEU A 186
LEU A 253
 None
 1.12A 1h9zA-3godA:
undetectable		 1h9zA-3godA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 248
GLY A 261
GLY A 260
VAL A 266
GLY A 245
 None
 0.91A 1n2xB-3godA:
undetectable		 1n2xB-3godA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  22
ASN A 230
TYR A 231
LEU A  59
 None
 1.12A 1qzrB-3godA:
undetectable		 1qzrB-3godA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  35
ILE A  52
LEU A  74
LEU A  23
LEU A  58
 None
 1.22A 2a15A-3godA:
undetectable		 2a15A-3godA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 225
PHE A 210
GLY A 219
GLY A 218
 None
 0.75A 2qx4A-3godA:
undetectable
2qx4B-3godA:
undetectable		 2qx4A-3godA:
23.88
2qx4B-3godA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 233
ALA A 237
THR A 241
LEU A 313
 None
 0.75A 2wx2A-3godA:
undetectable		 2wx2A-3godA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 233
ALA A 237
THR A 241
LEU A 313
 None
 0.79A 2wx2B-3godA:
undetectable		 2wx2B-3godA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 254
ALA A 267
ALA A 237
THR A 241
 MN  A 325 (-3.3A)
None
None
None
 1.02A 2xfhA-3godA:
undetectable		 2xfhA-3godA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3god CAS1
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 200
LEU A 197
ARG A 192
 None
 0.68A 3hcnB-3godA:
undetectable		 3hcnB-3godA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 233
ALA A 237
THR A 241
LEU A 313
 None
 0.69A 3khmA-3godA:
undetectable		 3khmA-3godA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 11 ILE A  66
ILE A  52
VAL A  81
VAL A  79
GLY A  78
 None
 0.81A 3kw4A-3godA:
0.2		 3kw4A-3godA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 233
ALA A 237
THR A 241
LEU A 313
 None
 0.78A 3l4dA-3godA:
undetectable		 3l4dA-3godA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 275
ARG A 285
ASP A 287
PHE A 292
LEU A 232
 None
 1.28A 3mjrA-3godA:
undetectable		 3mjrA-3godA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  87
ARG A 285
GLY A 219
ALA A 283
ASP A 287
 NA  A 326 (-4.5A)
None
None
None
None
 1.04A 3sugA-3godA:
undetectable		 3sugA-3godA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 189
GLY A 261
ARG A 258
GLY A 255
 None
 0.84A 5cdnA-3godA:
undetectable
5cdnB-3godA:
undetectable		 5cdnA-3godA:
21.77
5cdnB-3godA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 189
GLY A 261
ARG A 258
GLY A 255
 None
 0.76A 5cdnR-3godA:
undetectable
5cdnS-3godA:
undetectable		 5cdnR-3godA:
21.77
5cdnS-3godA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 189
GLY A 261
ARG A 258
GLY A 255
 None
 0.78A 5cdnC-3godA:
undetectable
5cdnD-3godA:
undetectable		 5cdnC-3godA:
21.77
5cdnD-3godA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 189
GLY A 261
ARG A 258
GLY A 255
 None
 0.80A 5cdnT-3godA:
undetectable
5cdnU-3godA:
undetectable		 5cdnT-3godA:
21.77
5cdnU-3godA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3god CAS1
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  52
GLY A  78
VAL A 101
CYH A  84
LEU A  59
 None
 1.17A 5ergB-3godA:
undetectable		 5ergB-3godA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 4 ASN A 299
LEU A 274
SER A 301
LEU A 236
 None
 1.35A 5kb5A-3godA:
undetectable		 5kb5A-3godA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3god CAS1
(Pseudomonas
aeruginosa) 		3 / 3 THR A  11
PRO A 106
ARG A  76
 None
 0.85A 5nd7B-3godA:
undetectable		 5nd7B-3godA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3god CAS1
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 237
THR A 241
ILE A 246
LEU A 313
 None
 0.89A 5te8A-3godA:
undetectable		 5te8A-3godA:
22.69