SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3goh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ALA A  66
LEU A 123
ALA A  86
LEU A 111
PRO A 112
 None
 1.01A 1mjqC-3gohA:
undetectable
1mjqD-3gohA:
undetectable		 1mjqC-3gohA:
14.42
1mjqD-3gohA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ALA A  66
LEU A 123
ALA A  86
LEU A 111
PRO A 112
 None
 1.01A 1mjqI-3gohA:
undetectable
1mjqJ-3gohA:
undetectable		 1mjqI-3gohA:
14.42
1mjqJ-3gohA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 7 ASN A  51
TYR A   9
ASN A  57
VAL A  16
 None
 1.34A 1wu8A-3gohA:
undetectable
1wu8C-3gohA:
undetectable		 1wu8A-3gohA:
21.60
1wu8C-3gohA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 5 LEU A 218
GLY A 222
HIS A 223
ILE A 224
 None
 0.98A 1xf1A-3gohA:
undetectable		 1xf1A-3gohA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 PHE A  97
ALA A 152
ALA A 122
PRO A  42
GLY A 151
 None
 1.27A 2igtC-3gohA:
6.6		 2igtC-3gohA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 7 ASP A  64
VAL A  63
PRO A 126
THR A 129
 None
 0.99A 2q6oA-3gohA:
undetectable		 2q6oA-3gohA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 6 ASP A  64
VAL A  63
PRO A 126
THR A 129
 None
 0.97A 2q6oB-3gohA:
undetectable		 2q6oB-3gohA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		3 / 3 GLY A  65
ASP A  64
SER A  96
 None
 0.64A 2qhfA-3gohA:
undetectable		 2qhfA-3gohA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.44A 2zj0B-3gohA:
9.3		 2zj0B-3gohA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.39A 2zj0C-3gohA:
9.3		 2zj0C-3gohA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 7 ILE A  38
ILE A 283
LEU A 312
LEU A 111
 None
 0.96A 3adxA-3gohA:
undetectable		 3adxA-3gohA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.47A 3ce6B-3gohA:
5.2		 3ce6B-3gohA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.41A 3glqA-3gohA:
9.2		 3glqA-3gohA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.44A 3glqB-3gohA:
8.2		 3glqB-3gohA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.41A 3n58C-3gohA:
8.3		 3n58C-3gohA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		3 / 3 GLN A  36
THR A 311
ASN A 313
 None
 0.90A 3v4tE-3gohA:
undetectable		 3v4tE-3gohA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 7 GLU A 302
ASP A 299
GLN A 303
ILE A  40
 None
 1.23A 4ii8A-3gohA:
undetectable		 4ii8A-3gohA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		4 / 8 ILE A  48
ILE A  40
ALA A 297
PRO A  61
 None
 0.64A 4jltA-3gohA:
undetectable		 4jltA-3gohA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		3 / 3 LYS A  92
TRP A  55
SER A  90
 None
 1.14A 5nwwA-3gohA:
undetectable		 5nwwA-3gohA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.46A 6f3nA-3gohA:
8.8		 6f3nA-3gohA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.39A 6f3nC-3gohA:
8.8		 6f3nC-3gohA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Shewanella
oneidensis) 		5 / 12 ASP A  64
LEU A 128
LEU A 250
GLY A 251
HIS A 254
 None
None
GOL  A 316 (-4.7A)
GOL  A 316 (-2.9A)
None
 1.46A 6f3nD-3gohA:
8.3		 6f3nD-3gohA:
21.52