SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 8 ARG A  15
GLU A 128
HIS A  47
SER A  51
 None
None
NI  A 200 (-3.5A)
None
 1.06A 1nx9A-3gorA:
undetectable		 1nx9A-3gorA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 8 ARG A  15
GLU A 128
HIS A  47
SER A  51
 None
None
NI  A 200 (-3.5A)
None
 1.05A 1nx9B-3gorA:
undetectable		 1nx9B-3gorA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 8 ARG A  15
GLU A 128
HIS A  47
SER A  51
 None
None
NI  A 200 (-3.5A)
None
 1.06A 1nx9C-3gorA:
undetectable		 1nx9C-3gorA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 8 ARG A  15
GLU A 128
HIS A  47
SER A  51
 None
None
NI  A 200 (-3.5A)
None
 1.08A 1nx9D-3gorA:
undetectable		 1nx9D-3gorA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		5 / 10 ALA A  41
ALA A  45
LEU A  49
LEU A  78
ALA A  82
 None
 1.17A 2bxeA-3gorA:
2.3		 2bxeA-3gorA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  44
HIS A 127
HIS A 131
HIS A  47
 None
NI  A 200 (-3.3A)
NI  A 200 (-3.4A)
NI  A 200 (-3.5A)
 1.35A 2oqeE-3gorA:
undetectable		 2oqeE-3gorA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 8 GLN A 134
HIS A 131
HIS A  47
HIS A 127
 None
NI  A 200 (-3.4A)
NI  A 200 (-3.5A)
NI  A 200 (-3.3A)
 1.05A 3w6hA-3gorA:
undetectable		 3w6hA-3gorA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		4 / 7 PHE A 150
HIS A  14
ILE A 129
TYR A  10
 None
 1.12A 4o7gA-3gorA:
undetectable
4o7gB-3gorA:
2.4		 4o7gA-3gorA:
20.78
4o7gB-3gorA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gor PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Geobacillus
stearothermophil
us) 		3 / 3 HIS A  47
HIS A 127
HIS A 131
 NI  A 200 (-3.5A)
NI  A 200 (-3.3A)
NI  A 200 (-3.4A)
 0.63A 6giqa-3gorA:
undetectable		 6giqa-3gorA:
14.02