SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3goz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
0.95A 1dhiA-3gozA:
undetectable
1dhiA-3gozA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
0.97A 1dhjA-3gozA:
undetectable
1dhjA-3gozA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
1.01A 1draA-3gozA:
undetectable
1draA-3gozA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
0.98A 1drbA-3gozA:
undetectable
1drbA-3gozA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 9 LEU A 162
ILE A 161
LEU A 187
GLY A 151
LEU A 174
None
1.14A 1e7aB-3gozA:
undetectable
1e7aB-3gozA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 11 SER A  11
ILE A  37
LEU A  34
LEU A   5
LEU A  29
None
1.12A 2a15A-3gozA:
undetectable
2a15A-3gozA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
1.00A 2drcA-3gozA:
undetectable
2drcA-3gozA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
3 / 3 ASP A 202
ARG A 146
ARG A 175
None
1.09A 2j9dA-3gozA:
undetectable
2j9dC-3gozA:
undetectable
2j9dA-3gozA:
15.43
2j9dC-3gozA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A  92
LEU A  85
ASN A  57
ILE A 107
LEU A 143
None
1.07A 3a50D-3gozA:
undetectable
3a50D-3gozA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A  58
GLY A  60
LEU A  56
SER A  55
None
0.80A 3aiaA-3gozA:
undetectable
3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A  87
GLY A  60
LEU A  85
SER A  84
None
0.96A 3aiaA-3gozA:
undetectable
3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A  87
GLY A  89
LEU A  85
SER A  84
None
0.71A 3aiaA-3gozA:
undetectable
3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A 145
GLY A 147
LEU A 143
SER A 142
None
0.80A 3aiaA-3gozA:
undetectable
3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A 174
GLY A 176
LEU A 172
SER A 171
None
0.80A 3aiaA-3gozA:
undetectable
3aiaA-3gozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 6 LEU A 245
ALA A 278
LEU A 248
SER A 251
None
1.02A 3cfqA-3gozA:
undetectable
3cfqA-3gozA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 SER A 251
LEU A 216
ILE A 194
LEU A 203
LEU A 174
None
1.08A 3cjtG-3gozA:
undetectable
3cjtG-3gozA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 SER A 251
LEU A 216
ILE A 194
LEU A 203
LEU A 174
None
1.09A 3cjtK-3gozA:
undetectable
3cjtK-3gozA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 179
SER A 193
ILE A 194
LEU A 201
ILE A 223
None
1.00A 3drcA-3gozA:
undetectable
3drcA-3gozA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
3 / 3 SER A  59
ASP A  28
ASN A   2
None
1.00A 3lslA-3gozA:
undetectable
3lslD-3gozA:
undetectable
3lslA-3gozA:
21.92
3lslD-3gozA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.10A 3n62A-3gozA:
undetectable
3n62A-3gozA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.14A 3n66B-3gozA:
undetectable
3n66B-3gozA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 11 ASN A 144
ARG A 146
ASN A 148
LEU A  87
LEU A 136
None
1.19A 3ndvC-3gozA:
undetectable
3ndvD-3gozA:
undetectable
3ndvC-3gozA:
23.65
3ndvD-3gozA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 5 LEU A 145
GLY A 117
PHE A 121
PHE A 133
None
1.14A 3smtA-3gozA:
undetectable
3smtA-3gozA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.12A 4d39A-3gozA:
undetectable
4d39A-3gozA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 7 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.13A 4d39B-3gozA:
undetectable
4d39B-3gozA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 9 ILE A 165
VAL A 113
LEU A 114
ILE A 111
PHE A 133
None
1.29A 4r38C-3gozA:
undetectable
4r38C-3gozA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 10 SER A 229
LEU A 191
SER A 200
LEU A 201
LEU A 179
None
1.04A 4yiaA-3gozA:
undetectable
4yiaA-3gozA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
3 / 3 ALA A 132
ASN A 135
LEU A 136
None
0.51A 5i1nC-3gozA:
undetectable
5i1nC-3gozA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A  71
LEU A  58
ASN A  57
ILE A 107
ILE A  78
None
1.08A 5itzB-3gozA:
undetectable
5itzB-3gozA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 7 ASP A 120
PHE A 121
GLY A 117
GLY A  89
None
0.91A 5n9xA-3gozA:
undetectable
5n9xA-3gozA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
3 / 3 ASP A 115
ASN A 144
ASP A 202
None
0.81A 5vopA-3gozA:
2.4
5vopA-3gozA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
3 / 3 ASP A 115
ASN A 144
ASP A 202
None
0.78A 5vopB-3gozA:
undetectable
5vopB-3gozA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.07A 5vunA-3gozA:
undetectable
5vunA-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.07A 5vunB-3gozA:
undetectable
5vunB-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.06A 5vuoB-3gozA:
undetectable
5vuoB-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
4 / 8 SER A 204
ARG A 175
ASN A 235
ASP A 261
None
1.11A 6auuB-3gozA:
undetectable
6auuB-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
6 / 12 GLU A 128
LEU A 143
LEU A 136
ALA A 132
SER A  97
LEU A 116
None
1.10A 6b0cD-3gozA:
2.3
6b0cD-3gozA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 ASN A 148
ASN A 177
LEU A 145
ASN A 144
GLY A  89
None
1.02A 6dwnA-3gozA:
undetectable
6dwnA-3gozA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
6 / 12 GLU A  41
LEU A  56
LEU A  85
ALA A  45
LEU A  27
LEU A   7
None
1.34A 6ew0B-3gozA:
undetectable
6ew0B-3gozA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
6 / 12 GLU A  41
LEU A  56
LEU A  85
ALA A  45
LEU A  27
LEU A   7
None
1.34A 6ew0D-3gozA:
undetectable
6ew0D-3gozA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
5 / 12 ASP A  98
GLU A  99
LEU A 114
SER A  68
LEU A  87
None
1.22A 6ew0F-3gozA:
undetectable
6ew0F-3gozA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
6 / 12 GLU A  41
LEU A  56
LEU A  85
ALA A  45
LEU A  27
LEU A   7
None
1.34A 6ew0H-3gozA:
undetectable
6ew0H-3gozA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila)
6 / 12 GLU A  41
LEU A  56
LEU A  85
ALA A  45
LEU A  27
LEU A   7
None
1.34A 6ew0I-3gozA:
undetectable
6ew0I-3gozA:
14.47