SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 11 SER A 114
HIS A 112
SER A  73
LEU A   7
ILE A 126
 None
GDP  A 138 ( 3.5A)
None
None
None
 1.17A 1ee2A-3gp9A:
undetectable		 1ee2A-3gp9A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 VAL A   6
ILE A   8
ILE A  21
ILE A  98
LEU A  88
 None
 1.04A 1qhyA-3gp9A:
undetectable		 1qhyA-3gp9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 10 VAL A   6
ALA A  12
VAL A  18
ILE A  72
ILE A  25
 None
 1.39A 3retA-3gp9A:
undetectable
3retB-3gp9A:
undetectable		 3retA-3gp9A:
20.00
3retB-3gp9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 GLN A  89
GLY A 100
GLY A  90
LEU A  93
ALA A 103
 MG  A 140 (-2.9A)
None
None
None
None
 1.27A 3sxjA-3gp9A:
undetectable		 3sxjA-3gp9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 GLN A  89
GLY A 100
GLY A  90
LEU A  93
ALA A 103
 MG  A 140 (-2.9A)
None
None
None
None
 1.27A 3sxjB-3gp9A:
undetectable		 3sxjB-3gp9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3gp9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 6 HIS A 112
GLU A 123
ASP A 115
SER A 119
 GDP  A 138 ( 3.5A)
None
None
None
 1.28A 4apjA-3gp9A:
undetectable
4apjP-3gp9A:
undetectable		 4apjA-3gp9A:
11.19
4apjP-3gp9A:
7.46