SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)
3gpr RHODOCETIN SUBUNIT
ALPHA

(Calloselasma
rhodostoma)
3 / 3 TRP A1067
VAL A1040
TRP A1023
None
1.34A 1c4dC-3gprA:
undetectable
1c4dD-3gprA:
undetectable
1c4dC-3gprA:
7.52
1c4dD-3gprA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)
3gpr RHODOCETIN SUBUNIT
DELTA

(Calloselasma
rhodostoma)
5 / 11 LEU D4058
VAL D4050
GLY D4051
LEU D4119
SER D4117
None
1.26A 2bxgA-3gprD:
undetectable
2bxgA-3gprD:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)
3gpr RHODOCETIN SUBUNIT
DELTA
RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
6 / 12 ALA D4048
GLY D4051
ASN C3095
GLY D4066
LEU D4065
LEU D4067
None
1.12A 2hw2A-3gprD:
undetectable
2hw2A-3gprD:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)
3gpr RHODOCETIN SUBUNIT
BETA

(Calloselasma
rhodostoma)
4 / 8 SER B2011
LEU B2013
TYR B2016
TYR B2014
None
1.00A 3i45A-3gprB:
undetectable
3i45A-3gprB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)
3gpr RHODOCETIN SUBUNIT
BETA

(Calloselasma
rhodostoma)
5 / 10 TYR B2066
ILE B2057
VAL B2101
TYR B2111
ILE B2044
None
1.50A 3uprA-3gprB:
undetectable
3uprA-3gprB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)
3gpr RHODOCETIN SUBUNIT
ALPHA

(Calloselasma
rhodostoma)
3 / 3 TRP A1067
VAL A1040
TRP A1023
None
1.24A 3zq8C-3gprA:
undetectable
3zq8D-3gprA:
undetectable
3zq8C-3gprA:
7.52
3zq8D-3gprA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
3 / 3 LYS C3124
LYS C3023
PRO C3022
None
1.15A 4dv1L-3gprC:
undetectable
4dv1L-3gprC:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
3 / 3 GLU C3029
TRP C3025
LYS C3130
None
1.45A 4k7aA-3gprC:
undetectable
4k7aA-3gprC:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
4 / 4 VAL C3068
ALA C3054
ILE C3061
THR C3058
None
1.20A 5e4dB-3gprC:
undetectable
5e4dB-3gprC:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
3 / 3 PRO C3064
ARG C3109
GLU C3065
None
0.96A 5j6hA-3gprC:
undetectable
5j6hA-3gprC:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
4 / 8 THR C3098
SER C3101
ASP C3074
SER C3082
None
1.01A 5l5fY-3gprC:
undetectable
5l5fZ-3gprC:
undetectable
5l5fY-3gprC:
17.14
5l5fZ-3gprC:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
3 / 3 VAL C3128
TYR C3016
GLN C3017
None
0.76A 5qgkA-3gprC:
undetectable
5qgkA-3gprC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
4 / 4 VAL C3042
VAL C3128
TYR C3016
GLN C3017
None
1.36A 5qgpA-3gprC:
undetectable
5qgpA-3gprC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
4 / 4 VAL C3042
VAL C3128
TYR C3016
GLN C3017
None
1.36A 5qgqA-3gprC:
undetectable
5qgqA-3gprC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
3 / 3 VAL C3128
TYR C3016
GLN C3017
None
0.75A 5qgrA-3gprC:
undetectable
5qgrA-3gprC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3gpr RHODOCETIN SUBUNIT
GAMMA

(Calloselasma
rhodostoma)
4 / 4 VAL C3042
VAL C3128
TYR C3016
GLN C3017
None
1.38A 5qhbA-3gprC:
undetectable
5qhbA-3gprC:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)
3gpr RHODOCETIN SUBUNIT
BETA

(Calloselasma
rhodostoma)
3 / 3 VAL B2100
TYR B2111
GLU B2117
None
0.95A 5zmqD-3gprB:
undetectable
5zmqE-3gprB:
undetectable
5zmqD-3gprB:
18.13
5zmqE-3gprB:
18.60