SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 ALA A 327
VAL A 325
TRP A 272
 None
 0.55A 1kqeA-3gq2A:
undetectable
1kqeE-3gq2A:
undetectable		 1kqeA-3gq2A:
2.26
1kqeE-3gq2A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 ALA A 327
VAL A 325
TRP A 272
 None
 0.57A 1kqeB-3gq2A:
undetectable
1kqeD-3gq2A:
undetectable		 1kqeB-3gq2A:
2.26
1kqeD-3gq2A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 TRP A 272
ALA A 327
VAL A 325
 None
 0.56A 1kqeB-3gq2A:
undetectable
1kqeD-3gq2A:
undetectable		 1kqeB-3gq2A:
2.26
1kqeD-3gq2A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 TRP A 272
ALA A 327
VAL A 325
 None
 0.58A 1kqeA-3gq2A:
undetectable
1kqeE-3gq2A:
undetectable		 1kqeA-3gq2A:
2.26
1kqeE-3gq2A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 ALA A 327
VAL A 325
TRP A 272
 None
 0.68A 1micA-3gq2A:
undetectable
1micB-3gq2A:
undetectable		 1micA-3gq2A:
2.68
1micB-3gq2A:
2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 5 LEU A 494
LEU A 497
LEU A 475
LEU A 474
 None
 0.95A 2ab2B-3gq2A:
undetectable		 2ab2B-3gq2A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 THR A 194
LEU A 193
GLU A 207
ALA A 209
LEU A 213
 None
 1.41A 2azqA-3gq2A:
undetectable		 2azqA-3gq2A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 12 VAL A 373
VAL A 366
THR A 406
GLY A 427
LEU A 448
 None
 1.15A 2cbrA-3gq2A:
undetectable		 2cbrA-3gq2A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 11 ILE A 624
LEU A 540
LEU A 581
ILE A 584
LEU A 616
 None
 1.32A 3a50C-3gq2A:
2.2		 3a50C-3gq2A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 12 LEU A 171
GLY A 142
GLY A  80
LEU A  69
ILE A  79
 None
 0.96A 3ku1H-3gq2A:
undetectable		 3ku1H-3gq2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		3 / 3 ALA A 440
VAL A 442
TRP A 438
 None
 0.82A 3l8lC-3gq2A:
undetectable
3l8lD-3gq2A:
undetectable		 3l8lC-3gq2A:
2.68
3l8lD-3gq2A:
2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 8 ILE A 584
GLN A 535
ALA A 542
LEU A 543
 None
 0.61A 3ozwA-3gq2A:
undetectable		 3ozwA-3gq2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 7 LEU A 146
ILE A 200
ILE A 203
LEU A 162
 None
 0.72A 3r9vA-3gq2A:
undetectable
3r9vB-3gq2A:
undetectable		 3r9vA-3gq2A:
19.45
3r9vB-3gq2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 LEU A 386
ALA A 440
VAL A 373
GLY A 422
ILE A 403
 None
 1.19A 3spkA-3gq2A:
undetectable		 3spkA-3gq2A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 PHE A 613
PHE A 609
VAL A 492
ILE A 584
GLY A 539
 None
 1.33A 3t3rB-3gq2A:
undetectable		 3t3rB-3gq2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 PHE A 613
PHE A 609
VAL A 492
ILE A 584
GLY A 539
 None
 1.29A 3t3rC-3gq2A:
undetectable		 3t3rC-3gq2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 10 PHE A 613
PHE A 609
VAL A 492
ILE A 584
GLY A 539
 None
 1.36A 3t3rD-3gq2A:
undetectable		 3t3rD-3gq2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 5 GLY A 110
SER A 111
PHE A 113
GLU A 115
 None
 0.94A 4m93B-3gq2A:
undetectable
4m93C-3gq2A:
undetectable		 4m93B-3gq2A:
16.93
4m93C-3gq2A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 6 VAL A 509
LEU A 513
PHE A 613
MET A 496
 None
 1.11A 4o1zA-3gq2A:
1.4		 4o1zA-3gq2A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 11 ARG A  73
LEU A  69
VAL A 138
LEU A 126
LEU A  86
 None
 1.11A 4or0B-3gq2A:
2.5		 4or0B-3gq2A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 LEU A 316
GLY A 311
VAL A 340
VAL A 287
LEU A 290
 None
 1.09A 4qd3A-3gq2A:
undetectable		 4qd3A-3gq2A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 5 ALA A 327
THR A 331
VAL A 385
ILE A 334
 None
 0.89A 4xe3A-3gq2A:
undetectable		 4xe3A-3gq2A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 5 ALA A 327
THR A 331
VAL A 385
ILE A 334
 None
 0.85A 4xe3B-3gq2A:
undetectable		 4xe3B-3gq2A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 9 LEU A 126
LEU A  65
LEU A  69
LEU A  83
ALA A  82
 None
 0.99A 5dqfA-3gq2A:
undetectable		 5dqfA-3gq2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 11 PHE A 134
ILE A 182
LEU A 188
GLY A 142
TYR A  87
 None
 1.39A 5fctA-3gq2A:
undetectable		 5fctA-3gq2A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		4 / 7 LEU A 458
THR A 500
ASP A 610
LEU A 474
 None
 1.10A 5jq7B-3gq2A:
undetectable		 5jq7B-3gq2A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115
(Bos
taurus) 		5 / 10 PHE A 351
ILE A 365
LEU A 407
LEU A 393
GLY A 399
 None
 1.48A 6r2eC-3gq2A:
undetectable		 6r2eC-3gq2A:
20.62