SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 114
GLY A 139
ILE A 165
ALA A 112
VAL A 107
 None
 0.95A 1jg2A-3gq9A:
undetectable		 1jg2A-3gq9A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 GLU A 181
GLU A 125
LEU A 155
 None
 0.67A 1v8bA-3gq9A:
undetectable		 1v8bA-3gq9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 1.04A 2e1qC-3gq9A:
undetectable		 2e1qC-3gq9A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ARG A 203
LYS A 202
LEU A 204
GLN A 206
 None
 1.01A 2eijP-3gq9A:
undetectable
2eijW-3gq9A:
undetectable		 2eijP-3gq9A:
17.13
2eijW-3gq9A:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 445
ILE A 498
GLY A 490
ILE A 463
ILE A 474
 None
 0.91A 2hs1B-3gq9A:
undetectable		 2hs1B-3gq9A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 GLY A 213
ARG A 215
TYR A 251
 None
 0.61A 2opxA-3gq9A:
undetectable		 2opxA-3gq9A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 366
GLY A 257
GLY A 255
GLY A 338
THR A 258
 None
 1.00A 2oxtA-3gq9A:
undetectable		 2oxtA-3gq9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 SER A 217
GLY A 241
HIS A 286
ASP A 280
 None
None
None
NA  A   1 ( 2.2A)
 1.10A 2oxtB-3gq9A:
undetectable		 2oxtB-3gq9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		6 / 12 GLY A 366
GLY A 257
GLY A 255
GLY A 338
THR A 258
VAL A 376
 None
 1.17A 2oxtD-3gq9A:
undetectable		 2oxtD-3gq9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 LEU A 320
VAL A 318
ILE A 346
ILE A 332
 None
 0.81A 2piwA-3gq9A:
undetectable		 2piwA-3gq9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ILE A 121
PRO A 150
LEU A 155
ILE A 128
 None
 1.01A 2q83B-3gq9A:
undetectable		 2q83B-3gq9A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 SER A 488
SER A 516
ASN A 519
GLY A 464
GLN A 437
 None
None
None
None
NHE  A 693 (-3.5A)
 1.34A 2x2iB-3gq9A:
undetectable		 2x2iB-3gq9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ASN A 393
LYS A 394
PRO A 300
PHE A 277
 None
 1.34A 3bjwD-3gq9A:
undetectable		 3bjwD-3gq9A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 587
GLY A 603
ILE A 570
SER A 592
SER A 573
 None
 1.31A 3gyqA-3gq9A:
undetectable
3gyqB-3gq9A:
undetectable		 3gyqA-3gq9A:
20.10
3gyqB-3gq9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ASN A 189
ILE A 190
GLU A 188
ASN A 266
 None
 1.16A 3kp6A-3gq9A:
undetectable
3kp6B-3gq9A:
undetectable		 3kp6A-3gq9A:
13.49
3kp6B-3gq9A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 SER A 604
SER A 592
THR A 606
SER A 607
 None
 1.48A 3loqA-3gq9A:
undetectable		 3loqA-3gq9A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ALA A 234
LEU A 219
ILE A 267
SER A 264
LEU A 192
 None
 1.20A 3nrrA-3gq9A:
undetectable		 3nrrA-3gq9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ALA A 234
LEU A 219
ILE A 267
SER A 264
LEU A 192
 None
 1.19A 3nrrB-3gq9A:
undetectable		 3nrrB-3gq9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ILE A 269
VAL A 318
THR A 284
ILE A 244
 None
 0.75A 3p4wC-3gq9A:
undetectable		 3p4wC-3gq9A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 GLY A 621
ILE A 646
ASP A 625
SER A 640
 None
 0.63A 3pwwA-3gq9A:
undetectable		 3pwwA-3gq9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 PHE A 124
LEU A 177
ALA A 163
LEU A 155
 None
 1.00A 3t3zD-3gq9A:
undetectable		 3t3zD-3gq9A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 SER A 325
SER A 388
LEU A 406
VAL A 408
PHE A 362
 None
 1.42A 3u9fB-3gq9A:
undetectable
3u9fC-3gq9A:
undetectable		 3u9fB-3gq9A:
14.89
3u9fC-3gq9A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 1.02A 3uniA-3gq9A:
undetectable		 3uniA-3gq9A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.45A 3v3nA-3gq9A:
undetectable		 3v3nA-3gq9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.45A 3v3nD-3gq9A:
undetectable		 3v3nD-3gq9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLY A 396
ASP A 399
ASN A 305
GLU A 333
 None
None
NA  A   1 (-3.9A)
None
 1.01A 3vywC-3gq9A:
undetectable		 3vywC-3gq9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 THR A 432
ASN A 458
GLY A 486
ILE A 474
 None
 0.95A 3w9tF-3gq9A:
undetectable		 3w9tF-3gq9A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 ASN A 307
GLY A 330
PHE A 397
SER A 325
GLY A 331
 NA  A   1 (-4.4A)
None
None
None
None
 1.30A 3ztvA-3gq9A:
undetectable		 3ztvA-3gq9A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 ASP A 312
THR A 283
GLU A 333
LYS A 335
 NA  A 692 (-3.3A)
None
None
NA  A 692 ( 4.0A)
 1.14A 4a3pA-3gq9A:
undetectable		 4a3pA-3gq9A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.43A 4a99D-3gq9A:
undetectable		 4a99D-3gq9A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 HIS A 286
GLY A 314
SER A 315
GLU A 310
 None
None
None
NA  A   1 ( 3.5A)
 0.93A 4hyfA-3gq9A:
undetectable		 4hyfA-3gq9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 HIS A 286
GLY A 314
SER A 315
GLU A 310
 None
None
None
NA  A   1 ( 3.5A)
 0.91A 4hyfB-3gq9A:
undetectable		 4hyfB-3gq9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 HIS A 286
GLY A 314
SER A 315
GLU A 310
 None
None
None
NA  A   1 ( 3.5A)
 0.92A 4hyfC-3gq9A:
undetectable		 4hyfC-3gq9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 TYR A 360
GLY A 308
GLY A 330
ILE A 282
SER A 325
 None
 1.08A 4iv0B-3gq9A:
undetectable		 4iv0B-3gq9A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 SER A 456
GLY A 531
ASP A 506
GLY A 503
 None
 0.68A 4koeA-3gq9A:
undetectable
4koeB-3gq9A:
undetectable
4koeC-3gq9A:
undetectable		 4koeA-3gq9A:
21.23
4koeB-3gq9A:
21.23
4koeC-3gq9A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 SER A 456
GLY A 531
ASP A 506
GLY A 503
 None
 0.71A 4koeA-3gq9A:
undetectable
4koeB-3gq9A:
undetectable
4koeD-3gq9A:
undetectable		 4koeA-3gq9A:
21.23
4koeB-3gq9A:
21.23
4koeD-3gq9A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 TYR A 360
GLY A 308
GLY A 330
ILE A 282
SER A 325
 None
 1.09A 4mwzA-3gq9A:
undetectable		 4mwzA-3gq9A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 ILE A 128
ARG A 145
ASP A 119
VAL A 136
 None
 1.24A 4nkxC-3gq9A:
undetectable		 4nkxC-3gq9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 ILE A 128
ARG A 145
ASP A 119
VAL A 136
 None
 1.23A 4nkxD-3gq9A:
undetectable		 4nkxD-3gq9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 192
ILE A 269
ILE A 282
GLY A 241
ILE A 229
 None
 0.79A 4q1xB-3gq9A:
undetectable		 4q1xB-3gq9A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 192
ILE A 269
ILE A 282
VAL A 227
ILE A 229
 None
 0.87A 4q1xB-3gq9A:
undetectable		 4q1xB-3gq9A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 445
ILE A 498
GLY A 490
ILE A 463
ILE A 474
 None
 0.90A 4q1yB-3gq9A:
undetectable		 4q1yB-3gq9A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 THR A 238
GLY A 212
GLY A 213
SER A 214
ASP A 243
 None
 0.96A 4qvwK-3gq9A:
undetectable
4qvwL-3gq9A:
undetectable		 4qvwK-3gq9A:
16.26
4qvwL-3gq9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 THR A 238
GLY A 212
GLY A 213
SER A 214
ASP A 243
 None
 0.96A 4qvwY-3gq9A:
undetectable
4qvwZ-3gq9A:
undetectable		 4qvwY-3gq9A:
16.26
4qvwZ-3gq9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 THR A 451
GLY A 507
ASP A 506
SER A 482
 None
 1.25A 4rfqA-3gq9A:
undetectable		 4rfqA-3gq9A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 428
GLY A 452
LEU A 479
ASN A 455
ARG A 390
 None
 1.25A 4x61A-3gq9A:
undetectable		 4x61A-3gq9A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 GLY A 546
ASP A 542
TYR A 543
ILE A 524
LEU A 547
 None
 1.14A 4xj7A-3gq9A:
undetectable
4xj7B-3gq9A:
undetectable		 4xj7A-3gq9A:
19.24
4xj7B-3gq9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLY A 531
ASP A 506
GLY A 503
SER A 456
 None
 0.68A 4z53A-3gq9A:
undetectable
4z53B-3gq9A:
undetectable		 4z53A-3gq9A:
21.09
4z53B-3gq9A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 GLY A 531
ASP A 506
GLY A 503
SER A 456
 None
 0.71A 4z53A-3gq9A:
undetectable
4z53B-3gq9A:
undetectable		 4z53A-3gq9A:
21.09
4z53B-3gq9A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 TYR A 422
THR A 420
THR A 451
 None
 0.81A 5aoxB-3gq9A:
undetectable		 5aoxB-3gq9A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 186
ASP A 243
SER A 217
THR A 283
HIS A 225
 None
 1.45A 5d0yA-3gq9A:
undetectable		 5d0yA-3gq9A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 503
ILE A 501
LEU A 527
GLY A 486
GLY A 452
 None
 0.98A 5d4uD-3gq9A:
undetectable		 5d4uD-3gq9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 366
GLY A 257
GLY A 255
GLY A 338
THR A 258
 None
 0.99A 5ehiC-3gq9A:
undetectable		 5ehiC-3gq9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 247
LEU A 219
PHE A 195
ILE A 165
THR A 153
 None
 1.18A 5eskA-3gq9A:
undetectable		 5eskA-3gq9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLU A 216
GLY A 210
ARG A 173
ARG A 301
 None
 1.39A 5jcnB-3gq9A:
undetectable		 5jcnB-3gq9A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ILE A 229
ILE A 290
ILE A 292
GLU A 270
 None
 0.73A 5mvmA-3gq9A:
undetectable
5mvmB-3gq9A:
undetectable		 5mvmA-3gq9A:
9.33
5mvmB-3gq9A:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 483
SER A 502
ILE A 501
GLY A 459
GLY A 486
 None
 0.92A 5wyqB-3gq9A:
undetectable		 5wyqB-3gq9A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		6 / 12 LEU A 192
LEU A 155
GLY A 146
ARG A 145
ASN A 187
PRO A 150
 None
 1.47A 6ce2B-3gq9A:
undetectable		 6ce2B-3gq9A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ASP A 280
ASP A 279
LYS A 335
TYR A 329
 NA  A   1 ( 2.2A)
NA  A   1 (-3.0A)
NA  A 692 ( 4.0A)
None
 1.46A 6g31G-3gq9A:
undetectable		 6g31G-3gq9A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3gq9 PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 ILE A 221
ILE A 242
GLU A 265
VAL A 227
ILE A 229
 None
 1.23A 6hloA-3gq9A:
undetectable		 6hloA-3gq9A:
21.14