SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_B_DCFB853_2 (ADENOSINE DEAMINASE)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	4 / 5	LEU B 555 SER B 546 LEU B 632 GLY B 553	None	0.96A	1a4lB-3gqiB: undetectable	1a4lB-3gqiB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_C_DCFC1353_2 (ADENOSINE DEAMINASE)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	4 / 5	LEU B 555 SER B 546 LEU B 632 GLY B 553	None	1.01A	1a4lC-3gqiB: undetectable	1a4lC-3gqiB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK1_A_T44A3001_1 (SERUM ALBUMIN)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	5 / 11	ARG B 684 LEU B 682 LEU B 692 HIS B 670 ALA B 760	None	1.37A	1hk1A-3gqiB: undetectable	1hk1A-3gqiB: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	4 / 5	VAL B 735 PHE B 691 ILE B 704 PHE B 706	None	1.12A	3owxB-3gqiB: undetectable	3owxB-3gqiB: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	3 / 3	ARG B 562 GLU B 589 THR B 590	None	0.80A	3v4tA-3gqiB: undetectable	3v4tA-3gqiB: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CZY_A_SAMA603_0 (LEGIONELLA EFFECTOR LEGAS4)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	5 / 12	LEU B 597 ARG B 586 SER B 546 TYR B 639 LEU B 653	None	1.09A	5czyA-3gqiB: undetectable	5czyA-3gqiB: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZMQ_K_PACK1_0 (SERINE PROTEASE NS3 PEPTIDE PAC-DLY-DLY-DAR)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	3 / 3	ALA B 662 VAL B 693 TYR B 669	None	0.67A	5zmqH-3gqiB: undetectable	5zmqH-3gqiB: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA825_0 (GEPHYRIN)	3gqi	PHOSPHOLIPASE C-GAMMA-1 (Rattus norvegicus)	3 / 3	LYS B 620 VAL B 628 ASP B 630	None	0.68A	6fgdA-3gqiB: undetectable	6fgdA-3gqiB: 19.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_B_DCFB853_2","ADENOSINE DEAMINASE","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",4,"LEU B 555;SER B 546;LEU B 632;GLY B 553","None","0.96A","1a4lB-3gqiB:undetectable","1a4lB-3gqiB:18.59"],["1A4L_C_DCFC1353_2","ADENOSINE DEAMINASE","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",4,"LEU B 555;SER B 546;LEU B 632;GLY B 553","None","1.01A","1a4lC-3gqiB:undetectable","1a4lC-3gqiB:18.59"],["1HK1_A_T44A3001_1","SERUM ALBUMIN","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",5,"ARG B 684;LEU B 682;LEU B 692;HIS B 670;ALA B 760","None","1.37A","1hk1A-3gqiB:undetectable","1hk1A-3gqiB:17.67"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",4,"VAL B 735;PHE B 691;ILE B 704;PHE B 706","None","1.12A","3owxB-3gqiB:undetectable","3owxB-3gqiB:21.61"],["3V4T_A_ACTA503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",3,"ARG B 562;GLU B 589;THR B 590","None","0.80A","3v4tA-3gqiB:undetectable","3v4tA-3gqiB:19.00"],["5CZY_A_SAMA603_0","LEGIONELLA EFFECTOR LEGAS4","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",5,"LEU B 597;ARG B 586;SER B 546;TYR B 639;LEU B 653","None","1.09A","5czyA-3gqiB:undetectable","5czyA-3gqiB:17.81"],["5ZMQ_K_PACK1_0","SERINE PROTEASE NS3;PEPTIDE PAC-DLY-DLY-DAR","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",3,"ALA B 662;VAL B 693;TYR B 669","None","0.67A","5zmqH-3gqiB:undetectable","5zmqH-3gqiB:23.40"],["6FGD_A_ACTA825_0","GEPHYRIN","3gqi","PHOSPHOLIPASE C-GAMMA-1","Rattus norvegicus",3,"LYS B 620;VAL B 628;ASP B 630","None","0.68A","6fgdA-3gqiB:undetectable","6fgdA-3gqiB:19.23"]]