SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 3gqk PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 ILE A 787
SER A 790
SER A 743
 ATP  A   1 (-3.6A)
None
None
 0.65A 3iltH-3gqkA:
undetectable		 3iltH-3gqkA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3gqk PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ASP A 692
VAL A 711
ILE A 718
SER A 732
 None
 0.99A 3pglA-3gqkA:
undetectable		 3pglA-3gqkA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3gqk PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 GLU A 741
TYR A 696
SER A 790
 None
 0.95A 4at0A-3gqkA:
undetectable		 4at0A-3gqkA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3gqk PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ILE A 818
ALA A 820
LEU A 710
ALA A 721
ILE A 832
 None
 0.99A 6a5yD-3gqkA:
undetectable		 6a5yD-3gqkA:
20.00