SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_B_FLPB701_1 (CYCLOOXYGENASE-2)	3gqx	NOP5P PROTEIN (Pyrococcus horikoshii)	5 / 11	ARG B 343 LEU B 270 LEU B 277 GLY B 336 ALA B 339	None None IOD B 3 ( 4.8A) None None	1.03A	3pghB-3gqxB: undetectable	3pghB-3gqxB: 16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_D_FLPD701_1 (CYCLOOXYGENASE-2)	3gqx	NOP5P PROTEIN (Pyrococcus horikoshii)	5 / 12	ARG B 343 LEU B 270 LEU B 277 GLY B 336 ALA B 339	None None IOD B 3 ( 4.8A) None None	1.03A	3pghD-3gqxB: undetectable	3pghD-3gqxB: 16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_B_SALB404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	3gqx	NOP5P PROTEIN (Pyrococcus horikoshii)	4 / 7	ALA B 333 TYR B 316 ARG B 327 ALA B 318	None	0.98A	3twpB-3gqxB: undetectable	3twpB-3gqxB: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_C_SALC404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	3gqx	NOP5P PROTEIN (Pyrococcus horikoshii)	4 / 7	ALA B 333 TYR B 316 ARG B 327 ALA B 318	None	1.06A	3twpC-3gqxB: undetectable	3twpC-3gqxB: 18.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3PGH_B_FLPB701_1","CYCLOOXYGENASE-2","3gqx","NOP5P PROTEIN","Pyrococcus horikoshii",5,"ARG B 343;LEU B 270;LEU B 277;GLY B 336;ALA B 339","None;None;IOD B   3 ( 4.8A);None;None","1.03A","3pghB-3gqxB:undetectable","3pghB-3gqxB:16.19"],["3PGH_D_FLPD701_1","CYCLOOXYGENASE-2","3gqx","NOP5P PROTEIN","Pyrococcus horikoshii",5,"ARG B 343;LEU B 270;LEU B 277;GLY B 336;ALA B 339","None;None;IOD B   3 ( 4.8A);None;None","1.03A","3pghD-3gqxB:undetectable","3pghD-3gqxB:16.19"],["3TWP_B_SALB404_1","ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE","3gqx","NOP5P PROTEIN","Pyrococcus horikoshii",4,"ALA B 333;TYR B 316;ARG B 327;ALA B 318","None","0.98A","3twpB-3gqxB:undetectable","3twpB-3gqxB:18.39"],["3TWP_C_SALC404_1","ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE","3gqx","NOP5P PROTEIN","Pyrococcus horikoshii",4,"ALA B 333;TYR B 316;ARG B 327;ALA B 318","None","1.06A","3twpC-3gqxB:undetectable","3twpC-3gqxB:18.39"]]