SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3gr5 ESCC
(Escherichia
coli) 		5 / 11 SER A 163
LEU A 166
ILE A 118
LEU A 122
VAL A 131
 None
 1.07A 3w67A-3gr5A:
undetectable		 3w67A-3gr5A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3gr5 ESCC
(Escherichia
coli) 		5 / 12 SER A 163
LEU A 166
ILE A 118
LEU A 122
VAL A 131
 None
 1.09A 3w68B-3gr5A:
undetectable		 3w68B-3gr5A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3gr5 ESCC
(Escherichia
coli) 		5 / 11 VAL A  63
SER A  62
GLU A 105
TYR A  87
LEU A  46
 None
 1.34A 5jh7B-3gr5A:
undetectable		 5jh7B-3gr5A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3gr5 ESCC
(Escherichia
coli) 		5 / 11 VAL A  63
SER A  62
GLU A 105
TYR A  87
LEU A  46
 None
 1.29A 5jh7D-3gr5A:
undetectable		 5jh7D-3gr5A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3gr5 ESCC
(Escherichia
coli) 		3 / 3 TRP A  91
GLU A  81
GLU A  25
 None
 0.97A 6fhwA-3gr5A:
undetectable		 6fhwA-3gr5A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 3gr5 ESCC
(Escherichia
coli) 		4 / 5 SER A 130
VAL A 131
LYS A 133
ASN A 137
 None
 1.41A 6fi4A-3gr5A:
undetectable
6fi4B-3gr5A:
undetectable		 6fi4A-3gr5A:
20.34
6fi4B-3gr5A:
10.00