SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3grh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		3 / 3 ARG A 387
ASP A 268
ASN A 215
 None
 0.88A 1nbhA-3grhA:
undetectable		 1nbhA-3grhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		3 / 3 ARG A 387
ASP A 268
ASN A 215
 None
 0.86A 1nbhD-3grhA:
undetectable		 1nbhD-3grhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 7 PHE A 267
VAL A 228
GLY A 261
VAL A 329
 None
 0.99A 1t88A-3grhA:
undetectable		 1t88A-3grhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 11 PHE A 272
SER A 303
ILE A 331
PHE A 305
PHE A 286
 None
 1.30A 3a9eB-3grhA:
undetectable		 3a9eB-3grhA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 7 TRP A 174
TRP A 134
LYS A 160
ASN A 235
 None
 1.21A 3k8mA-3grhA:
undetectable		 3k8mA-3grhA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 7 ASP A   5
GLN A   6
PRO A   3
GLN A   1
 None
 0.89A 3l2vA-3grhA:
undetectable		 3l2vA-3grhA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 ARG A  14
PHE A 340
GLY A 311
ALA A 335
GLY A 388
 None
 1.27A 3v3oA-3grhA:
undetectable		 3v3oA-3grhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 ARG A  14
PHE A 340
GLY A 311
ALA A 335
GLY A 388
 None
 1.16A 3v3oB-3grhA:
undetectable		 3v3oB-3grhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 11 ARG A  14
PHE A 340
GLY A 311
ALA A 335
GLY A 388
 None
 1.08A 4a6nA-3grhA:
undetectable		 4a6nA-3grhA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 8 ASN A 326
VAL A 329
SER A 318
ALA A 357
 None
 0.98A 4eyzA-3grhA:
undetectable		 4eyzA-3grhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 8 ASN A 326
VAL A 329
SER A 318
ALA A 357
 None
 0.98A 4eyzB-3grhA:
undetectable		 4eyzB-3grhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 9 ASP A 257
VAL A 203
ALA A 204
GLY A 261
PHE A 227
 None
 1.17A 4mmfA-3grhA:
undetectable		 4mmfA-3grhA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 9 ASP A 257
VAL A 203
ALA A 204
GLY A 261
PHE A 227
 None
 1.21A 4mmfB-3grhA:
undetectable		 4mmfB-3grhA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 ALA A 202
GLN A 223
GLY A 254
ASP A 193
TYR A 251
 None
 1.14A 4pclA-3grhA:
undetectable		 4pclA-3grhA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 5 LEU A 291
SER A 292
ASP A 320
ASP A 348
 None
 1.22A 4qtuD-3grhA:
undetectable		 4qtuD-3grhA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 6 SER A 170
ARG A 262
GLY A 261
THR A 325
 None
 1.01A 5btaA-3grhA:
undetectable
5btaB-3grhA:
undetectable
5btaC-3grhA:
undetectable		 5btaA-3grhA:
21.83
5btaB-3grhA:
19.01
5btaC-3grhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 6 SER A 170
ARG A 262
GLY A 261
THR A 325
 None
 1.06A 5btcA-3grhA:
undetectable
5btcB-3grhA:
undetectable
5btcC-3grhA:
undetectable		 5btcA-3grhA:
21.83
5btcB-3grhA:
19.01
5btcC-3grhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		3 / 3 ARG A 273
PHE A 226
LEU A 220
 None
 0.78A 5veuA-3grhA:
undetectable		 5veuA-3grhA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 GLY A 221
GLY A 192
THR A 225
GLU A 253
ILE A 187
 None
 0.90A 5wz1B-3grhA:
undetectable		 5wz1B-3grhA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 GLY A 221
GLY A 192
THR A 225
GLU A 253
ILE A 187
 None
 0.94A 5wz2C-3grhA:
undetectable		 5wz2C-3grhA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 GLY A 209
ALA A 102
PRO A 243
THR A 207
PHE A 226
 None
 1.27A 5x6yA-3grhA:
undetectable		 5x6yA-3grhA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 10 ILE A  16
LEU A  17
PHE A  25
LEU A 299
ALA A 300
 None
 1.25A 5y7pD-3grhA:
undetectable		 5y7pD-3grhA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		5 / 12 VAL A 285
SER A 260
PHE A 267
PHE A 298
VAL A 247
 None
 1.42A 6a94A-3grhA:
undetectable		 6a94A-3grhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3grh ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		3 / 3 TYR A 154
ASP A 155
GLN A 158
 None
 0.93A 6g1pA-3grhA:
undetectable		 6g1pA-3grhA:
20.93