SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3grn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 5 PHE A 126
TYR A  12
VAL A  85
ASP A  39
 None
 1.34A 1dz6B-3grnA:
undetectable		 1dz6B-3grnA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 7 PHE A 129
PHE A 130
PHE A  22
VAL A  89
 None
 1.01A 1lh6A-3grnA:
undetectable		 1lh6A-3grnA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 8 PHE A 133
PHE A 130
PHE A 129
ALA A  13
 None
 0.88A 3t3sD-3grnA:
undetectable		 3t3sD-3grnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 8 TYR A  12
VAL A  76
LEU A  24
LEU A 122
 None
 0.92A 4jtrA-3grnA:
undetectable		 4jtrA-3grnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 6 GLU A 104
ARG A  27
GLU A  62
GLU A  58
 GOL  A 154 ( 3.3A)
GOL  A 154 ( 4.7A)
GOL  A 154 ( 4.9A)
GOL  A 154 (-3.0A)
 1.40A 4kr3A-3grnA:
undetectable		 4kr3A-3grnA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 6 LYS A   5
PRO A   6
LEU A  80
GLU A  79
 None
 1.41A 4z4cA-3grnA:
undetectable		 4z4cA-3grnA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		5 / 10 PRO A  41
ILE A 116
LEU A  23
SER A 109
GLU A 107
 None
 1.44A 5tixB-3grnA:
undetectable		 5tixB-3grnA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 5 MET A  67
TYR A  12
GLY A  42
GLY A  43
 None
None
None
GOL  A 154 ( 3.7A)
 0.66A 5x7pA-3grnA:
undetectable		 5x7pA-3grnA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 6 MET A  67
TYR A  12
GLY A  42
GLY A  43
 None
None
None
GOL  A 154 ( 3.7A)
 0.62A 5x7pB-3grnA:
undetectable		 5x7pB-3grnA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		4 / 8 LEU A  80
ASN A  34
PHE A 129
LEU A  40
 None
 0.84A 5y7pC-3grnA:
undetectable		 5y7pC-3grnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3grn MUTT RELATED PROTEIN
(Methanosarcina
mazei) 		5 / 12 VAL A  89
LEU A 117
LEU A 113
ARG A 127
LEU A  24
 None
 1.24A 6ew0F-3grnA:
undetectable		 6ew0F-3grnA:
20.00