SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3grz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 VAL A 183
GLY A 184
ASP A 206
ILE A 207
ILE A 253
 GOL  A 322 ( 4.9A)
GOL  A 322 ( 3.7A)
GOL  A 322 (-3.5A)
GOL  A 322 (-4.1A)
GOL  A 322 ( 4.7A)
 0.67A 1cetA-3grzA:
6.0		 1cetA-3grzA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.31A 1jhoA-3grzA:
undetectable		 1jhoA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.31A 1jhrA-3grzA:
undetectable		 1jhrA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.30A 1jhyA-3grzA:
undetectable		 1jhyA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.31A 1l4nA-3grzA:
undetectable		 1l4nA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.30A 1l5kA-3grzA:
undetectable		 1l5kA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 THR A 163
GLY A 184
GLY A 186
THR A 205
ASN A 248
 None
GOL  A 322 ( 3.7A)
None
GOL  A 322 (-4.1A)
None
 0.80A 1nv8A-3grzA:
16.0		 1nv8A-3grzA:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 LEU A 244
LEU A 178
LEU A 265
ILE A 309
ARG A 172
 None
 1.09A 1tw4A-3grzA:
undetectable		 1tw4A-3grzA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 LEU A 244
LEU A 178
LEU A 265
ILE A 309
ARG A 172
 None
 1.16A 1tw4B-3grzA:
undetectable		 1tw4B-3grzA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		3 / 3 GLY A 184
ASP A 206
ASN A 248
 GOL  A 322 ( 3.7A)
GOL  A 322 (-3.5A)
None
 0.24A 1vq1A-3grzA:
16.0		 1vq1A-3grzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 MET A 167
ALA A 166
ASN A 248
GLY A 169
ILE A 170
 None
 1.40A 2dcfA-3grzA:
undetectable		 2dcfA-3grzA:
20.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		6 / 12 ASP A 182
GLY A 184
GLY A 186
LEU A 190
ILE A 207
ASN A 248
 None
GOL  A 322 ( 3.7A)
None
None
GOL  A 322 (-4.1A)
None
 0.60A 2nxeA-3grzA:
26.6		 2nxeA-3grzA:
30.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		6 / 12 ASP A 182
GLY A 184
GLY A 186
LEU A 190
ILE A 207
ASN A 248
 None
GOL  A 322 ( 3.7A)
None
None
GOL  A 322 (-4.1A)
None
 0.58A 2nxeB-3grzA:
26.9		 2nxeB-3grzA:
30.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 LEU A 255
ILE A 258
ALA A 247
PHE A 273
LEU A 261
 None
 1.04A 2qb4A-3grzA:
undetectable		 2qb4A-3grzA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 11 LEU A 255
ILE A 258
ALA A 247
PHE A 273
LEU A 261
 None
 1.04A 2qjuA-3grzA:
undetectable		 2qjuA-3grzA:
21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 184
GLY A 186
LEU A 190
ILE A 207
ASN A 248
 GOL  A 322 ( 3.7A)
None
None
GOL  A 322 (-4.1A)
None
 0.60A 2zbpA-3grzA:
26.2		 2zbpA-3grzA:
30.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 11 MET A 167
ALA A 166
ASN A 248
GLY A 169
ILE A 170
 None
 1.42A 2zmaA-3grzA:
undetectable		 2zmaA-3grzA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		3 / 3 GLY A 186
ASP A 206
SER A 208
 None
GOL  A 322 (-3.5A)
None
 0.57A 3brfA-3grzA:
undetectable		 3brfA-3grzA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 ASP A 182
GLY A 184
LEU A 190
ASP A 206
ILE A 207
 None
GOL  A 322 ( 3.7A)
None
GOL  A 322 (-3.5A)
GOL  A 322 (-4.1A)
 0.38A 3cjtC-3grzA:
25.1		 3cjtC-3grzA:
29.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		6 / 12 GLY A 184
GLY A 186
SER A 187
LEU A 190
ILE A 207
ASN A 248
 GOL  A 322 ( 3.7A)
None
None
None
GOL  A 322 (-4.1A)
None
 0.41A 3cjtG-3grzA:
25.1		 3cjtG-3grzA:
29.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 184
SER A 187
LEU A 190
ILE A 207
ASN A 248
 GOL  A 322 ( 3.7A)
None
None
GOL  A 322 (-4.1A)
None
 0.42A 3cjtK-3grzA:
25.2		 3cjtK-3grzA:
29.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		6 / 12 GLY A 184
GLY A 186
SER A 187
LEU A 190
ILE A 207
ASN A 248
 GOL  A 322 ( 3.7A)
None
None
None
GOL  A 322 (-4.1A)
None
 0.39A 3cjtO-3grzA:
25.2		 3cjtO-3grzA:
29.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 ILE A 170
ILE A 189
ILE A 122
LEU A 165
VAL A 246
 None
 1.04A 3fpjB-3grzA:
14.3		 3fpjB-3grzA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		3 / 3 ASP A 143
PHE A 141
SER A 125
 None
 1.01A 3i5uB-3grzA:
9.7		 3i5uB-3grzA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 THR A 163
GLY A 184
ASP A 206
LEU A 234
ASN A 248
 None
GOL  A 322 ( 3.7A)
GOL  A 322 (-3.5A)
GOL  A 322 (-4.4A)
None
 0.73A 3q87B-3grzA:
16.7		 3q87B-3grzA:
26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 11 ASP A 182
GLY A 184
GLY A 186
ASP A 206
ASN A 248
 None
GOL  A 322 ( 3.7A)
None
GOL  A 322 (-3.5A)
None
 0.53A 4dcmA-3grzA:
18.3		 4dcmA-3grzA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 THR A 163
GLY A 158
GLY A 188
LEU A 190
SER A 187
 None
 1.31A 4kqiA-3grzA:
undetectable		 4kqiA-3grzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 186
ASP A 206
ILE A 207
SER A 233
ASN A 248
 None
GOL  A 322 (-3.5A)
GOL  A 322 (-4.1A)
GOL  A 322 ( 4.3A)
None
 0.60A 4pooB-3grzA:
16.3		 4pooB-3grzA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 184
GLY A 186
ILE A 207
SER A 208
LEU A 234
 GOL  A 322 ( 3.7A)
None
GOL  A 322 (-4.1A)
None
GOL  A 322 (-4.4A)
 0.68A 4qdjA-3grzA:
16.8		 4qdjA-3grzA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 158
GLY A 186
ASP A 206
ILE A 207
SER A 233
 None
None
GOL  A 322 (-3.5A)
GOL  A 322 (-4.1A)
GOL  A 322 ( 4.3A)
 0.63A 4rtsA-3grzA:
10.9		 4rtsA-3grzA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 9 SER A 211
ALA A 215
ALA A 219
GLY A 184
ALA A 204
 None
None
None
GOL  A 322 ( 3.7A)
None
 1.09A 5d0xY-3grzA:
undetectable
5d0xZ-3grzA:
undetectable		 5d0xY-3grzA:
23.40
5d0xZ-3grzA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 ILE A 189
GLY A 186
SER A 187
VAL A 238
LEU A 203
 None
 1.14A 5ergB-3grzA:
14.1		 5ergB-3grzA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 12 GLY A 184
GLY A 186
ASP A 206
ILE A 207
SER A 233
 GOL  A 322 ( 3.7A)
None
GOL  A 322 (-3.5A)
GOL  A 322 (-4.1A)
GOL  A 322 ( 4.3A)
 0.43A 5wy0A-3grzA:
12.7		 5wy0A-3grzA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Lactobacillus
delbrueckii) 		5 / 10 THR A 163
ASP A 182
GLY A 184
GLY A 186
ASN A 248
 None
None
GOL  A 322 ( 3.7A)
None
None
 1.08A 6nqaK-3grzA:
8.8		 6nqaK-3grzA:
19.18