SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gt2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
3gt2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium)
4 / 6 SER A  88
GLY A  86
LEU A 122
TYR A 125
None
0.95A 1fduD-3gt2A:
undetectable
1fduD-3gt2A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)
3gt2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium)
5 / 12 GLY A 109
GLY A 116
GLY A  98
LEU A 122
VAL A  92
None
1.12A 2wa2A-3gt2A:
undetectable
2wa2A-3gt2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)
3gt2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium)
4 / 4 GLY A 145
VAL A 200
GLY A 139
THR A 166
None
0.90A 3ib2A-3gt2A:
undetectable
3ib2A-3gt2A:
17.08