SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ARG A 102
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.09A 1d4yA-3gt7A:
undetectable		 1d4yA-3gt7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.19A 1muiB-3gt7A:
undetectable		 1muiB-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ARG A 102
GLY A 107
ALA A 108
ASP A 109
VAL A  63
 None
 0.84A 2aquA-3gt7A:
undetectable		 2aquA-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.10A 2aquB-3gt7A:
undetectable		 2aquB-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
 None
 1.02A 2b7zA-3gt7A:
undetectable		 2b7zA-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
 None
 0.98A 2b7zB-3gt7A:
undetectable		 2b7zB-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.26A 2fxeB-3gt7A:
undetectable		 2fxeB-3gt7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
VAL A  63
 None
 0.88A 2ieoA-3gt7A:
undetectable		 2ieoA-3gt7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.19A 2o4kB-3gt7A:
undetectable		 2o4kB-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.19A 2o4lB-3gt7A:
undetectable		 2o4lB-3gt7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 11 ARG A 102
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.10A 2o4pA-3gt7A:
undetectable		 2o4pA-3gt7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		4 / 7 LYS A 114
LEU A  90
ASP A  62
SER A 103
 None
 0.94A 3dzgA-3gt7A:
3.1		 3dzgA-3gt7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ARG A 102
GLY A 107
ALA A 108
ASP A 109
VAL A  63
 None
 0.97A 3ekyA-3gt7A:
undetectable		 3ekyA-3gt7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
VAL A  63
 None
 0.95A 3el1A-3gt7A:
undetectable		 3el1A-3gt7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.13A 3el1B-3gt7A:
undetectable		 3el1B-3gt7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
 None
 1.07A 3el9B-3gt7A:
undetectable		 3el9B-3gt7A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  89
 None
 1.00A 3el9B-3gt7A:
undetectable		 3el9B-3gt7A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.08A 3em4A-3gt7A:
undetectable		 3em4A-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.11A 3em4U-3gt7A:
undetectable		 3em4U-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 0.96A 3lzvA-3gt7A:
undetectable		 3lzvA-3gt7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.03A 3ndxA-3gt7A:
undetectable		 3ndxA-3gt7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 11 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.15A 3ndxB-3gt7A:
undetectable		 3ndxB-3gt7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 LEU A  83
GLU A  46
ALA A  47
SER A  52
LEU A  15
 None
 1.22A 3ou6D-3gt7A:
2.1		 3ou6D-3gt7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 0.98A 3oxwC-3gt7A:
undetectable		 3oxwC-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 11 ARG A 102
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.11A 3oxxB-3gt7A:
undetectable		 3oxxB-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.12A 3oxxC-3gt7A:
undetectable		 3oxxC-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  89
 None
 1.01A 3oxxC-3gt7A:
undetectable		 3oxxC-3gt7A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		4 / 8 ARG A 102
GLY A 107
ALA A 108
ASP A 109
 None
 0.53A 4eyrB-3gt7A:
undetectable		 4eyrB-3gt7A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 TYR A  71
CYH A 106
LEU A  91
VAL A  63
LEU A  73
 None
 1.12A 4k36B-3gt7A:
undetectable		 4k36B-3gt7A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 11 TYR A  71
CYH A 106
LEU A  91
VAL A  63
LEU A  73
 None
 1.11A 4k37A-3gt7A:
undetectable		 4k37A-3gt7A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 TYR A  71
CYH A 106
LEU A  91
VAL A  63
LEU A  73
 None
 1.03A 4k38B-3gt7A:
undetectable		 4k38B-3gt7A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 0.94A 6dh0A-3gt7A:
undetectable		 6dh0A-3gt7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 0.92A 6dh6A-3gt7A:
undetectable		 6dh6A-3gt7A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 3gt7 SENSOR PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ARG A 102
GLY A 107
ALA A 108
ASP A 109
ILE A  59
VAL A  63
 None
 1.27A 6dj2B-3gt7A:
undetectable		 6dj2B-3gt7A:
21.05