SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 6 ALA A 114
ILE A 186
PRO A 144
GLU A 143
 SAH  A 401 (-4.4A)
None
None
None
 1.19A 1oniB-3gu3A:
undetectable
1oniC-3gu3A:
undetectable		 1oniB-3gu3A:
17.50
1oniC-3gu3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 11 GLY A  47
GLY A  49
ILE A  70
ASP A  97
ALA A  98
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
None
SAH  A 401 (-3.3A)
SAH  A 401 (-3.3A)
 0.62A 3dxyA-3gu3A:
13.8		 3dxyA-3gu3A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
ASP A  71
ALA A  98
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
SAH  A 401 (-4.4A)
 0.66A 3g89A-3gu3A:
14.8		 3g89A-3gu3A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 11 GLY A  47
GLY A  49
ASP A  71
ALA A  98
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
SAH  A 401 (-4.4A)
 0.66A 3g89B-3gu3A:
14.7		 3g89B-3gu3A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
ASP A  71
ALA A  98
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
SAH  A 401 (-4.4A)
 0.60A 3g8bA-3gu3A:
14.6		 3g8bA-3gu3A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
ASP A  71
ALA A  98
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
SAH  A 401 (-4.4A)
 0.67A 3g8bB-3gu3A:
13.3		 3g8bB-3gu3A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		3 / 3 GLY A  49
ASP A  71
ASP A  97
 SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
 0.28A 3ou7C-3gu3A:
15.4		 3ou7C-3gu3A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
GLY A  51
ALA A  98
THR A  99
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
None
SAH  A 401 (-3.3A)
SAH  A 401 ( 4.0A)
 0.66A 4uckA-3gu3A:
7.1		 4uckA-3gu3A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		4 / 4 ASP A  45
GLY A  49
ASP A  71
ASP A  97
 SAH  A 401 ( 4.5A)
SAH  A 401 (-3.3A)
SAH  A 401 (-2.7A)
SAH  A 401 (-3.3A)
 0.66A 5e72A-3gu3A:
14.1		 5e72A-3gu3A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ASP A  97
ALA A  98
PHE A 115
GLY A  49
SER A  72
 SAH  A 401 (-3.3A)
SAH  A 401 (-3.3A)
SAH  A 401 (-4.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-3.6A)
 0.84A 5hfjE-3gu3A:
4.1		 5hfjE-3gu3A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
LEU A  53
THR A  99
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
None
SAH  A 401 ( 4.0A)
SAH  A 401 (-4.4A)
 0.73A 5kpcA-3gu3A:
13.3		 5kpcA-3gu3A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 GLY A  47
GLY A  49
ASP A  97
THR A  99
ALA A 114
 SAH  A 401 (-3.8A)
SAH  A 401 (-3.3A)
SAH  A 401 (-3.3A)
SAH  A 401 ( 4.0A)
SAH  A 401 (-4.4A)
 0.67A 5kpcB-3gu3A:
13.4		 5kpcB-3gu3A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 3gu3 METHYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ASN A  32
ILE A  37
VAL A  41
ILE A 109
PRO A  88
 None
 1.13A 6hlpA-3gu3A:
4.6		 6hlpA-3gu3A:
20.53