SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 10 PHE A 232
VAL A 322
VAL A 326
ILE A 119
LEU A 157
 None
 1.27A 1fe2A-3guxA:
undetectable		 1fe2A-3guxA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 12 ALA A 253
GLY A 257
GLY A 259
ALA A 321
THR A 318
 None
 1.15A 2c49A-3guxA:
undetectable		 2c49A-3guxA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 12 ASP A 174
ILE A 119
ARG A 118
GLU A 245
GLY A 219
 None
 1.34A 5il1A-3guxA:
2.0		 5il1A-3guxA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 12 ASP A 174
ILE A 119
ARG A 118
GLU A 245
GLY A 219
 None
 1.36A 5k7uA-3guxA:
2.3		 5k7uA-3guxA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 12 VAL A 322
ILE A 160
ILE A 220
LEU A 157
VAL A 225
 None
 0.95A 5uvmB-3guxA:
undetectable		 5uvmB-3guxA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 226
GLY A 155
GLY A 153
ILE A 160
ALA A  49
 None
 0.94A 5x7fA-3guxA:
undetectable		 5x7fA-3guxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		4 / 7 ASN A 106
GLY A 150
ALA A 151
LEU A  76
 None
 0.73A 6dwnB-3guxA:
undetectable		 6dwnB-3guxA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		4 / 7 ASP A  45
ARG A 162
LYS A 320
GLN A 324
 None
 1.40A 6g31A-3guxA:
undetectable		 6g31A-3guxA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3gux PUTATIVE
ZN-DEPENDENT
EXOPEPTIDASE
(Bacteroides
vulgatus) 		4 / 7 ASP A  45
ARG A 162
LYS A 320
GLN A 324
 None
 1.17A 6g31G-3guxA:
undetectable		 6g31G-3guxA:
12.38