SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3guy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		3 / 3 GLU A 138
TYR A 141
PHE A  83
 None
 0.97A 1eqbB-3guyA:
2.8		 1eqbB-3guyA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		3 / 3 GLU A 138
TYR A 141
PHE A  83
 None
 0.96A 1eqbA-3guyA:
2.7		 1eqbA-3guyA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		3 / 3 GLU A 138
TYR A 141
PHE A  83
 None
 0.97A 1eqbD-3guyA:
2.8		 1eqbD-3guyA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		3 / 3 GLU A 138
TYR A 141
PHE A  83
 None
 0.97A 1eqbC-3guyA:
2.8		 1eqbC-3guyA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		4 / 8 ARG A 115
LYS A 114
ARG A 110
VAL A  60
 None
 1.33A 1u1jA-3guyA:
3.7		 1u1jA-3guyA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		4 / 6 PHE A  64
TYR A 116
LEU A 112
THR A   5
 None
 1.21A 4paeA-3guyA:
undetectable		 4paeA-3guyA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		5 / 12 ILE A   2
LEU A 205
VAL A 124
LEU A   1
LEU A  67
 None
 1.23A 6b54A-3guyA:
1.9		 6b54A-3guyA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		4 / 4 ILE A   4
LEU A  11
HIS A 202
ALA A 198
 None
 1.00A 6ck2C-3guyA:
undetectable
6ck2D-3guyA:
undetectable		 6ck2C-3guyA:
7.18
6ck2D-3guyA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3guy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Vibrio
parahaemolyticus) 		3 / 3 LEU A  63
ASN A  46
LEU A   1
 None
 0.76A 6exiD-3guyA:
6.6		 6exiD-3guyA:
18.01