SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		3 / 3 ARG A 204
THR A 225
VAL A 192
 None
 0.93A 1hxbA-3gv0A:
undetectable		 1hxbA-3gv0A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 4 GLY A 305
LEU A 303
GLY A  89
ARG A 306
 None
 0.77A 1j7kA-3gv0A:
undetectable		 1j7kA-3gv0A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 7 VAL A 251
THR A 258
LEU A 261
VAL A 276
 None
 0.95A 1jgsA-3gv0A:
undetectable		 1jgsA-3gv0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 GLY A 255
SER A 256
ILE A 233
ILE A 278
LEU A 261
 None
 1.07A 1kyvA-3gv0A:
7.1
1kyvE-3gv0A:
7.1		 1kyvA-3gv0A:
24.07
1kyvE-3gv0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 ILE A 278
LEU A 261
GLY A 255
SER A 256
ILE A 233
 None
 1.08A 1kyvD-3gv0A:
7.2
1kyvE-3gv0A:
7.0		 1kyvD-3gv0A:
24.07
1kyvE-3gv0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 4 GLY A 255
SER A 252
VAL A 262
LEU A 287
 None
 1.27A 1yajB-3gv0A:
2.4		 1yajB-3gv0A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 6 PHE A  82
GLN A 282
ASN A 298
LEU A 180
 None
 1.26A 2nyrA-3gv0A:
3.7		 2nyrA-3gv0A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		3 / 3 ARG A 204
THR A 225
VAL A 192
 None
 0.96A 2qakA-3gv0A:
undetectable		 2qakA-3gv0A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 7 ASP A  76
SER A  74
LYS A 132
GLU A 134
 None
 1.15A 3bc9A-3gv0A:
undetectable		 3bc9A-3gv0A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 ALA A  70
GLY A 127
LEU A 101
PHE A 150
LEU A  73
 None
 1.33A 3bxoA-3gv0A:
3.9		 3bxoA-3gv0A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		3 / 3 GLU A 227
HIS A 108
HIS A 106
 None
 0.54A 3co4A-3gv0A:
undetectable		 3co4A-3gv0A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 LEU A 230
GLY A 237
LEU A 240
ILE A 272
ILE A 290
 None
 1.10A 3ijdA-3gv0A:
undetectable		 3ijdA-3gv0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 LEU A 230
GLY A 237
LEU A 240
ILE A 272
ILE A 290
 None
 1.15A 3ijdB-3gv0A:
undetectable		 3ijdB-3gv0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 4 GLY A 206
TYR A 174
GLY A 210
ASP A 213
 None
 1.13A 3kl3A-3gv0A:
undetectable		 3kl3A-3gv0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 5 LEU A 120
GLY A 123
THR A  66
VAL A  68
 None
 1.08A 3wrkD-3gv0A:
undetectable		 3wrkD-3gv0A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 GLY A 210
ARG A 204
ILE A 211
GLU A 218
VAL A 177
 None
 1.23A 4azsA-3gv0A:
3.2		 4azsA-3gv0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 GLY A 210
ARG A 204
ILE A 211
GLU A 218
VAL A 177
 None
 1.22A 4azwA-3gv0A:
undetectable		 4azwA-3gv0A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 7 LEU A  71
LEU A 313
LEU A 308
ILE A 316
 None
 1.05A 4okwA-3gv0A:
undetectable		 4okwA-3gv0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		5 / 12 GLY A 264
ALA A 267
ILE A 259
SER A 256
ASP A 235
 None
 1.22A 4rtpA-3gv0A:
undetectable		 4rtpA-3gv0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 6 ILE A 191
GLY A 206
ASN A 208
ILE A 253
 None
 0.92A 5j4nB-3gv0A:
undetectable		 5j4nB-3gv0A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Agrobacterium
fabrum) 		4 / 9 VAL A 270
VAL A 279
SER A 280
ASP A 277
 None
 0.79A 6c2mD-3gv0A:
undetectable		 6c2mD-3gv0A:
14.24