SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 125
LYS A 139
ALA A 141
PRO A 238
 None
 0.23A 3gv1A-3gv1A:
32.0
3gv1C-3gv1A:
30.0		 3gv1A-3gv1A:
100.00
3gv1C-3gv1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 6 LEU A 125
LYS A 139
ALA A 141
PRO A 238
 None
 0.00A 3gv1A-3gv1A:
32.0
3gv1B-3gv1A:
29.9		 3gv1A-3gv1A:
100.00
3gv1B-3gv1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 LEU A 125
ALA A 141
VAL A 236
PRO A 238
 None
 0.11A 3gv1B-3gv1A:
29.9		 3gv1B-3gv1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 8 PRO A 216
VAL A 217
GLN A 190
ILE A 129
 None
 1.02A 4iilA-3gv1A:
2.2		 4iilA-3gv1A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L64_A_C2FA802_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 7 LYS A 160
SER A 247
TYR A 246
ARG A 153
 None
 1.50A 4l64A-3gv1A:
undetectable		 4l64A-3gv1A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ASN A 215
ILE A 212
SER A 211
GLY A 210
ARG A 193
 None
 1.16A 4xt8A-3gv1A:
undetectable		 4xt8A-3gv1A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		5 / 9 VAL A 142
VAL A 140
PHE A 237
ILE A 255
LEU A 154
 None
 1.30A 5e4dA-3gv1A:
undetectable		 5e4dA-3gv1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 8 GLY A 175
ASP A 145
ASP A 147
PRO A 149
 None
None
None
BEZ  A 302 (-4.2A)
 0.83A 6ag0A-3gv1A:
undetectable		 6ag0A-3gv1A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3gv1 DISULFIDE
INTERCHANGE PROTEIN
(Neisseria
gonorrhoeae) 		4 / 8 GLY A 175
ASP A 145
ASP A 147
PRO A 149
 None
None
None
BEZ  A 302 (-4.2A)
 0.79A 6ag0C-3gv1A:
undetectable		 6ag0C-3gv1A:
18.71