SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.83A 1c9sT-3gveA:
undetectable
1c9sU-3gveA:
undetectable		 1c9sT-3gveA:
12.61
1c9sU-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 TYR A  98
PHE A 124
ARG A  48
THR A 324
 None
 1.01A 1ea1A-3gveA:
undetectable		 1ea1A-3gveA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.74A 1fb7A-3gveA:
undetectable		 1fb7A-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.85A 1gtfL-3gveA:
undetectable
1gtfM-3gveA:
undetectable		 1gtfL-3gveA:
12.61
1gtfM-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.85A 1gtfN-3gveA:
undetectable
1gtfO-3gveA:
undetectable		 1gtfN-3gveA:
12.61
1gtfO-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 1hshC-3gveA:
undetectable		 1hshC-3gveA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.76A 1muiA-3gveA:
undetectable		 1muiA-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.79A 1muiB-3gveA:
undetectable		 1muiB-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		3 / 3 ASP A  61
HIS A 106
HIS A  18
 MG  A 403 ( 2.7A)
CIT  A 502 (-3.9A)
MN  A 402 (-3.4A)
 0.69A 1oe3A-3gveA:
undetectable		 1oe3A-3gveA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ASN A 138
ASN A 128
ILE A 165
GLY A 166
 None
 1.08A 1oniA-3gveA:
undetectable
1oniB-3gveA:
undetectable		 1oniA-3gveA:
18.18
1oniB-3gveA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ASN A 138
ASN A 128
ILE A 165
GLY A 166
 None
 1.12A 1oniD-3gveA:
undetectable
1oniF-3gveA:
0.5		 1oniD-3gveA:
18.18
1oniF-3gveA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.71A 1rl8A-3gveA:
undetectable		 1rl8A-3gveA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.67A 1rl8B-3gveA:
undetectable		 1rl8B-3gveA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.84A 1sdtB-3gveA:
undetectable		 1sdtB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.85A 1sduB-3gveA:
undetectable		 1sduB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 1sdvB-3gveA:
undetectable		 1sdvB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 LEU A 291
ALA A 301
LEU A 289
SER A 303
 None
 1.33A 1tyrA-3gveA:
undetectable		 1tyrA-3gveA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.75A 2aquA-3gveA:
undetectable		 2aquA-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.75A 2aquB-3gveA:
undetectable		 2aquB-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 2avvB-3gveA:
undetectable		 2avvB-3gveA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.84A 2avvE-3gveA:
undetectable		 2avvE-3gveA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.63A 2b60A-3gveA:
undetectable		 2b60A-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.74A 2b60B-3gveA:
undetectable		 2b60B-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 2f81B-3gveA:
undetectable		 2f81B-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A 103
GLY A  60
LEU A  62
ILE A  63
ILE A 126
 None
 0.85A 2f8dA-3gveA:
undetectable		 2f8dA-3gveA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A 103
GLY A  60
LEU A  62
ILE A  63
ILE A 126
 None
 0.83A 2f8dB-3gveA:
undetectable		 2f8dB-3gveA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.69A 2fxeA-3gveA:
undetectable		 2fxeA-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.81A 2fxeB-3gveA:
undetectable		 2fxeB-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.78A 2hs1A-3gveA:
undetectable		 2hs1A-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.67A 2hs2B-3gveA:
undetectable		 2hs2B-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 9 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.59A 2idwB-3gveA:
undetectable		 2idwB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 2ienB-3gveA:
undetectable		 2ienB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.73A 2nmyA-3gveA:
undetectable		 2nmyA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 2nmzA-3gveA:
undetectable		 2nmzA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ILE A 208
ILE A 239
ASN A 128
VAL A 127
 None
 0.69A 2nniA-3gveA:
undetectable		 2nniA-3gveA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.78A 2o4kB-3gveA:
undetectable		 2o4kB-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 2o4sA-3gveA:
undetectable		 2o4sA-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.70A 2o4sB-3gveA:
undetectable		 2o4sB-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.75A 2pynA-3gveA:
undetectable		 2pynA-3gveA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 2q63A-3gveA:
undetectable		 2q63A-3gveA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.71A 2q64A-3gveA:
undetectable		 2q64A-3gveA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.84A 2qakA-3gveA:
undetectable		 2qakA-3gveA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.70A 2qhcB-3gveA:
undetectable		 2qhcB-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 2r5pD-3gveA:
undetectable		 2r5pD-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.79A 2r5qB-3gveA:
undetectable		 2r5qB-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 2r5qD-3gveA:
undetectable		 2r5qD-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.73A 2rkfA-3gveA:
undetectable		 2rkfA-3gveA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.81A 2rkfB-3gveA:
undetectable		 2rkfB-3gveA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.82A 2rkgA-3gveA:
undetectable		 2rkgA-3gveA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 THR A 328
THR A 332
HIS A  87
VAL A  92
MET A  93
 None
 1.38A 2vaxC-3gveA:
0.0		 2vaxC-3gveA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 THR A 328
THR A 332
HIS A  87
VAL A  92
MET A  93
 None
 1.37A 2vaxD-3gveA:
0.0		 2vaxD-3gveA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 THR A 328
THR A 332
HIS A  87
VAL A  92
MET A  93
 None
 1.39A 2vaxG-3gveA:
undetectable		 2vaxG-3gveA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 THR A 328
THR A 332
HIS A  87
VAL A  92
MET A  93
 None
 1.37A 2vaxL-3gveA:
0.0		 2vaxL-3gveA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		3 / 3 ASP A  61
HIS A 106
HIS A  18
 MG  A 403 ( 2.7A)
CIT  A 502 (-3.9A)
MN  A 402 (-3.4A)
 0.70A 2xxgA-3gveA:
undetectable		 2xxgA-3gveA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		3 / 3 ASP A  61
HIS A 106
HIS A  18
 MG  A 403 ( 2.7A)
CIT  A 502 (-3.9A)
MN  A 402 (-3.4A)
 0.70A 2xxgC-3gveA:
undetectable		 2xxgC-3gveA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.76A 2z54A-3gveA:
undetectable		 2z54A-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.75A 2z54B-3gveA:
undetectable		 2z54B-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		3 / 3 MET A  93
GLU A 107
ASN A 105
 None
None
MG  A 403 ( 2.6A)
 0.93A 3a27A-3gveA:
undetectable		 3a27A-3gveA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 GLY A 117
ILE A  80
ILE A  90
ASP A 116
 None
 0.97A 3a7eA-3gveA:
undetectable		 3a7eA-3gveA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ALA A 233
LEU A 232
ALA A 210
ASN A  59
 None
 0.79A 3b6hA-3gveA:
undetectable		 3b6hA-3gveA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ALA A 233
LEU A 232
ALA A 210
ASN A  59
 None
 0.82A 3b6hB-3gveA:
undetectable		 3b6hB-3gveA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 3bvbB-3gveA:
undetectable		 3bvbB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A  62
LEU A  56
ALA A 122
ILE A  44
THR A 320
 None
 1.05A 3c6gA-3gveA:
undetectable		 3c6gA-3gveA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 3cywB-3gveA:
undetectable		 3cywB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.84A 3d1yA-3gveA:
undetectable		 3d1yA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.62A 3d1zB-3gveA:
undetectable		 3d1zB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.60A 3d20B-3gveA:
undetectable		 3d20B-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A 210
ALA A 212
ILE A 239
THR A 236
 None
 0.87A 3dtuC-3gveA:
undetectable
3dtuD-3gveA:
undetectable		 3dtuC-3gveA:
20.61
3dtuD-3gveA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.70A 3ekqA-3gveA:
undetectable		 3ekqA-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 3ektC-3gveA:
undetectable		 3ektC-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.70A 3ektD-3gveA:
undetectable		 3ektD-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.65A 3ekvA-3gveA:
undetectable		 3ekvA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.67A 3ekwB-3gveA:
undetectable		 3ekwB-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.82A 3ekyA-3gveA:
undetectable		 3ekyA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 GLY A 121
ALA A 122
ASP A 123
ILE A 126
 None
 0.37A 3el0A-3gveA:
undetectable		 3el0A-3gveA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.80A 3el1B-3gveA:
undetectable		 3el1B-3gveA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.59A 3jvyB-3gveA:
undetectable		 3jvyB-3gveA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.81A 3jw2A-3gveA:
undetectable		 3jw2A-3gveA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.53A 3jw2B-3gveA:
undetectable		 3jw2B-3gveA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.77A 3k4vD-3gveA:
undetectable		 3k4vD-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.76A 3lzuB-3gveA:
undetectable		 3lzuB-3gveA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ILE A 165
ALA A 210
ALA A 233
THR A 236
 None
 1.05A 3mdrB-3gveA:
undetectable		 3mdrB-3gveA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 TYR A 283
VAL A 321
VAL A 314
ILE A  44
 None
 0.94A 3mssB-3gveA:
undetectable		 3mssB-3gveA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.68A 3mwsA-3gveA:
undetectable		 3mwsA-3gveA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.82A 3ndtA-3gveA:
undetectable		 3ndtA-3gveA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.72A 3ndtD-3gveA:
undetectable		 3ndtD-3gveA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 3nduA-3gveA:
undetectable		 3nduA-3gveA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.78A 3nduB-3gveA:
undetectable		 3nduB-3gveA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.78A 3nduD-3gveA:
undetectable		 3nduD-3gveA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.65A 3ndxA-3gveA:
undetectable		 3ndxA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.76A 3ndxB-3gveA:
undetectable		 3ndxB-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.70A 3oxcA-3gveA:
undetectable		 3oxcA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.60A 3pwmB-3gveA:
undetectable		 3pwmB-3gveA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.65A 3s45B-3gveA:
undetectable		 3s45B-3gveA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.69A 3s54B-3gveA:
undetectable		 3s54B-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 4 PHE A  35
TYR A  24
ILE A  44
LEU A  43
 None
 1.28A 3sudA-3gveA:
undetectable		 3sudA-3gveA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 5 PHE A  35
TYR A  24
ILE A  44
LEU A  43
 None
 1.27A 3sueC-3gveA:
undetectable		 3sueC-3gveA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 GLY A 121
ALA A 122
ASP A 123
ILE A  89
 None
 0.55A 3t3cA-3gveA:
undetectable		 3t3cA-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 224
GLN A 171
ASP A 188
GLU A 226
ALA A 228
 None
 0.83A 3t7sA-3gveA:
undetectable		 3t7sA-3gveA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 224
GLN A 171
ASP A 188
GLU A 226
ALA A 228
 None
 0.79A 3t7sB-3gveA:
undetectable		 3t7sB-3gveA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 224
GLN A 171
ASP A 188
GLU A 226
ALA A 228
 None
 0.78A 3t7sD-3gveA:
undetectable		 3t7sD-3gveA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.63A 3tkgA-3gveA:
undetectable		 3tkgA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.63A 3tkgC-3gveA:
undetectable		 3tkgC-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.62A 3tkwA-3gveA:
undetectable		 3tkwA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.74A 3tl9A-3gveA:
undetectable		 3tl9A-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		6 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
LEU A 103
ILE A 126
 None
 0.88A 3ttpA-3gveA:
undetectable		 3ttpA-3gveA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 3ttpB-3gveA:
undetectable		 3ttpB-3gveA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 9 GLY A 121
ALA A 122
ASP A 123
ILE A  89
LEU A 103
 None
 0.99A 3u7sB-3gveA:
undetectable		 3u7sB-3gveA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ILE A 287
LEU A 289
VAL A 162
GLY A 163
 None
 0.89A 3w1wA-3gveA:
undetectable		 3w1wA-3gveA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.61A 4dqfB-3gveA:
undetectable		 4dqfB-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.73A 4hlaA-3gveA:
undetectable		 4hlaA-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 11 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.69A 4hlaB-3gveA:
undetectable		 4hlaB-3gveA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 TYR A 140
ILE A 119
ASP A  58
GLY A 101
 None
 0.85A 4iqqA-3gveA:
undetectable		 4iqqA-3gveA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 4jecA-3gveA:
undetectable		 4jecA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.68A 4ll3B-3gveA:
undetectable		 4ll3B-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.69A 4ll3A-3gveA:
undetectable		 4ll3A-3gveA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		3 / 3 PHE A 124
THR A  40
LEU A  62
 None
 0.73A 4qztA-3gveA:
0.6		 4qztA-3gveA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 LEU A 291
ALA A 301
LEU A 289
SER A 303
 None
 1.26A 5a6iA-3gveA:
undetectable		 5a6iA-3gveA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.66A 5e5jA-3gveA:
undetectable		 5e5jA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.65A 5e5kA-3gveA:
undetectable		 5e5kA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.83A 5eezL-3gveA:
undetectable
5eezV-3gveA:
undetectable		 5eezL-3gveA:
12.61
5eezV-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.83A 5ef1L-3gveA:
undetectable
5ef1V-3gveA:
undetectable		 5ef1L-3gveA:
12.61
5ef1V-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  72
THR A 332
HIS A 329
THR A 328
 None
 0.83A 5ef2L-3gveA:
undetectable
5ef2V-3gveA:
undetectable		 5ef2L-3gveA:
12.61
5ef2V-3gveA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.85A 5kqxA-3gveA:
undetectable		 5kqxA-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 GLY A 121
ALA A 122
ASP A 123
ILE A  89
 None
 0.59A 5kqyB-3gveA:
undetectable		 5kqyB-3gveA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 8 GLY A 121
ALA A 122
ASP A 123
ILE A  89
 None
 0.64A 5kr1B-3gveA:
undetectable		 5kr1B-3gveA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 6 ASP A  61
ASP A  16
HIS A  18
HIS A 248
HIS A 213
 MG  A 403 ( 2.7A)
MN  A 402 (-3.2A)
MN  A 402 (-3.4A)
MN  A 402 (-3.4A)
MG  A 403 (-3.5A)
 1.12A 5ncdA-3gveA:
undetectable
5ncdD-3gveA:
undetectable		 5ncdA-3gveA:
23.04
5ncdD-3gveA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 6 ASP A  61
ASP A  16
HIS A  18
HIS A 248
HIS A 213
 MG  A 403 ( 2.7A)
MN  A 402 (-3.2A)
MN  A 402 (-3.4A)
MN  A 402 (-3.4A)
MG  A 403 (-3.5A)
 1.11A 5ncdB-3gveA:
undetectable
5ncdC-3gveA:
undetectable		 5ncdB-3gveA:
23.04
5ncdC-3gveA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 6 ASP A  61
ASP A  16
HIS A  18
HIS A 248
HIS A 213
 MG  A 403 ( 2.7A)
MN  A 402 (-3.2A)
MN  A 402 (-3.4A)
MN  A 402 (-3.4A)
MG  A 403 (-3.5A)
 1.07A 5nelA-3gveA:
undetectable
5nelD-3gveA:
undetectable		 5nelA-3gveA:
23.04
5nelD-3gveA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 6 ASP A  61
HIS A  18
HIS A 248
HIS A 213
 MG  A 403 ( 2.7A)
MN  A 402 (-3.4A)
MN  A 402 (-3.4A)
MG  A 403 (-3.5A)
 1.03A 5nelB-3gveA:
undetectable
5nelC-3gveA:
undetectable		 5nelB-3gveA:
23.04
5nelC-3gveA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 TYR A 140
ILE A 119
ASP A  58
GLY A 101
 None
 0.83A 5nooA-3gveA:
undetectable		 5nooA-3gveA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.74A 5t2zA-3gveA:
undetectable		 5t2zA-3gveA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 5t2zB-3gveA:
undetectable		 5t2zB-3gveA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.64A 5t8hA-3gveA:
undetectable		 5t8hA-3gveA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		4 / 7 HIS A  87
GLN A  76
MET A  21
THR A 328
 None
 1.48A 5u6mA-3gveA:
undetectable		 5u6mA-3gveA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.61A 6dgxA-3gveA:
undetectable		 6dgxA-3gveA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.60A 6dh3A-3gveA:
undetectable		 6dh3A-3gveA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 121
ALA A 122
ASP A 123
ILE A  89
ILE A 126
 None
 0.79A 6dj1A-3gveA:
undetectable		 6dj1A-3gveA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3gve YFKN PROTEIN
(Bacillus
subtilis) 		5 / 9 ILE A 216
GLN A 247
GLU A 226
VAL A 229
ILE A 269
 None
 1.23A 6hloA-3gveA:
undetectable		 6hloA-3gveA:
20.93