SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.88A 1p7lD-3gvyA:
undetectable		 1p7lD-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.90A 1p7lC-3gvyA:
undetectable		 1p7lC-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.87A 1rg9B-3gvyA:
undetectable		 1rg9B-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.86A 1rg9A-3gvyA:
undetectable		 1rg9A-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.87A 1rg9D-3gvyA:
undetectable		 1rg9D-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.88A 1rg9C-3gvyA:
undetectable		 1rg9C-3gvyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		3 / 3 SER A  48
THR A  86
GLN A  32
 None
 0.85A 2fk8A-3gvyA:
undetectable		 2fk8A-3gvyA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 SER A 116
ILE A   8
LEU A  11
GLY A  67
 None
 0.73A 3dcjB-3gvyA:
undetectable		 3dcjB-3gvyA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 5 TYR A 133
GLN A 137
ILE A 144
LEU A 140
 None
 1.02A 3ls4L-3gvyA:
undetectable		 3ls4L-3gvyA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 5 ALA A  93
GLU A  51
GLU A 127
ALA A  21
 None
FE  A 163 (-2.5A)
FE  A 163 (-2.0A)
None
 1.43A 3r9tC-3gvyA:
undetectable		 3r9tC-3gvyA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		5 / 9 LEU A  58
LEU A 123
ILE A  49
GLU A  50
GLU A  94
 None
None
None
None
FE  A 163 ( 4.5A)
 1.09A 3tmzA-3gvyA:
1.4		 3tmzA-3gvyA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 5 HIS A 130
LEU A  58
LEU A  19
ASP A  56
 None
 1.15A 4aqlA-3gvyA:
undetectable		 4aqlA-3gvyA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		5 / 12 HIS A  28
TRP A  35
LEU A  27
GLU A  85
ALA A  89
 None
 0.97A 4hfpD-3gvyA:
undetectable		 4hfpD-3gvyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.91A 4kttB-3gvyA:
undetectable		 4kttB-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.82A 4kttB-3gvyA:
undetectable		 4kttB-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.85A 4kttD-3gvyA:
undetectable		 4kttD-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.82A 4kttD-3gvyA:
undetectable		 4kttD-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		3 / 3 ASP A  90
TRP A  35
SER A  44
 None
 1.10A 4lrhF-3gvyA:
undetectable		 4lrhF-3gvyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.89A 4ndnB-3gvyA:
undetectable		 4ndnB-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.83A 4ndnB-3gvyA:
undetectable		 4ndnB-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.80A 4ndnD-3gvyA:
undetectable		 4ndnD-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.78A 4ndnD-3gvyA:
undetectable		 4ndnD-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.85A 5t8sA-3gvyA:
undetectable		 5t8sA-3gvyA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.86A 5t8sA-3gvyA:
undetectable		 5t8sA-3gvyA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 7 ALA A  97
GLU A 127
ASP A 132
ASP A  90
 None
FE  A 163 (-2.0A)
None
None
 0.82A 6fbnA-3gvyA:
undetectable		 6fbnA-3gvyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3gvy BACTERIOFERRITIN
(Rhodobacter
sphaeroides) 		4 / 7 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE  A 163 (-2.0A)
None
None
 0.81A 6fbnA-3gvyA:
undetectable		 6fbnA-3gvyA:
15.70