SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gvz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		4 / 4 ALA A  96
GLN A 187
TYR A 177
LEU A 103
 None
 1.42A 1e6wC-3gvzA:
undetectable		 1e6wC-3gvzA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 11 LEU A 212
ALA A 259
ALA A 240
LEU A 254
GLN A 255
 None
 1.28A 1iiuA-3gvzA:
undetectable		 1iiuA-3gvzA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 12 LEU A  68
THR A 283
LEU A 256
GLY A 268
PHE A 276
 None
 1.30A 1v8bD-3gvzA:
undetectable		 1v8bD-3gvzA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		4 / 4 LEU A  99
PRO A 100
LEU A 103
ARG A 160
 None
 1.25A 2qd2A-3gvzA:
undetectable		 2qd2A-3gvzA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		4 / 6 LEU A 218
ALA A  43
LEU A  41
ALA A  31
 None
 0.88A 2vcvB-3gvzA:
undetectable		 2vcvB-3gvzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		4 / 6 LEU A 218
ALA A  43
LEU A  41
ALA A  31
 None
 0.83A 2vcvK-3gvzA:
undetectable		 2vcvK-3gvzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		4 / 4 LEU A  99
PRO A 100
LEU A 103
ARG A 160
 None
 1.06A 3hcoB-3gvzA:
undetectable		 3hcoB-3gvzA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		3 / 3 SER A 168
GLY A 169
GLN A 166
 None
 0.61A 3v4tH-3gvzA:
undetectable		 3v4tH-3gvzA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 12 TYR A 177
GLY A 156
LEU A 183
ALA A 130
LEU A 163
 None
 1.15A 3vywA-3gvzA:
undetectable		 3vywA-3gvzA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 12 TYR A 177
GLY A 156
LEU A 183
ALA A 130
LEU A 163
 None
 1.14A 3vywB-3gvzA:
undetectable		 3vywB-3gvzA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 12 TYR A 177
GLY A 156
LEU A 183
ALA A 130
LEU A 163
 None
 1.14A 3vywD-3gvzA:
undetectable		 3vywD-3gvzA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		3 / 3 LYS A  26
THR A 174
ILE A 189
 None
 0.91A 4e0fB-3gvzA:
undetectable		 4e0fB-3gvzA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 11 LEU A 143
VAL A  91
PHE A 134
LEU A 163
LEU A 123
 None
 1.36A 4zbqA-3gvzA:
undetectable		 4zbqA-3gvzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 11 PHE A 215
TRP A 242
LEU A  68
ASP A 269
ALA A 271
 None
 0.85A 5fctA-3gvzA:
undetectable		 5fctA-3gvzA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3gvz UNCHARACTERIZED
PROTEIN CV2077
(Chromobacterium
violaceum) 		5 / 11 PHE A 215
TRP A 242
LEU A  68
ASP A 269
ALA A 271
 None
 1.02A 6r2eF-3gvzA:
undetectable		 6r2eF-3gvzA:
24.44