SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gw4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 GLU A  93
HIS A  71
ASP A 103
 None
 0.53A 1i9gA-3gw4A:
undetectable		 1i9gA-3gw4A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 MET A  75
GLU A  93
ASP A 103
 None
 0.75A 3a25A-3gw4A:
undetectable		 3a25A-3gw4A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 ALA A 167
GLU A 166
LEU A 157
ARG A 128
LEU A 119
 None
 1.18A 4j24D-3gw4A:
undetectable		 4j24D-3gw4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 MET A 191
ASP A 176
PHE A 151
 None
 1.04A 4xeyA-3gw4A:
undetectable		 4xeyA-3gw4A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 MET A 191
ASP A 176
PHE A 151
 None
 1.02A 4xeyB-3gw4A:
undetectable		 4xeyB-3gw4A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 GLU A  93
HIS A  71
ASP A 103
 None
 0.58A 5c0oG-3gw4A:
undetectable		 5c0oG-3gw4A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3gw4 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 TRP A  83
ARG A  78
LEU A 119
 None
 0.89A 5dbyA-3gw4A:
undetectable		 5dbyA-3gw4A:
17.04