SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3gw6	ENDO-N-ACETYLNEURAMI NIDASE (Enterobacteria phage K1F)	3 / 3	GLN A 853 THR A 850 THR A 849	None	0.75A	4fu9A-3gw6A: undetectable	4fu9A-3gw6A: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUF_A_ACTA310_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3gw6	ENDO-N-ACETYLNEURAMI NIDASE (Enterobacteria phage K1F)	3 / 3	GLN A 853 THR A 850 THR A 849	None	0.77A	4fufA-3gw6A: undetectable	4fufA-3gw6A: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7J_A_5FWA401_0 (BETA-1 ADRENERGIC RECEPTOR)	3gw6	ENDO-N-ACETYLNEURAMI NIDASE (Enterobacteria phage K1F)	5 / 12	ASP A 994 VAL A 996 SER A 848 ASN A 870 TYR A 857	None	1.22A	6h7jA-3gw6A: undetectable	6h7jA-3gw6A: 12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7J_B_5FWB402_0 (BETA-1 ADRENERGIC RECEPTOR)	3gw6	ENDO-N-ACETYLNEURAMI NIDASE (Enterobacteria phage K1F)	5 / 12	ASP A 994 VAL A 996 SER A 848 ASN A 870 TYR A 857	None	1.22A	6h7jB-3gw6A: undetectable	6h7jB-3gw6A: 12.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FU9_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3gw6","ENDO-N-ACETYLNEURAMINIDASE","Enterobacteria phage K1F",3,"GLN A 853;THR A 850;THR A 849","None","0.75A","4fu9A-3gw6A:undetectable","4fu9A-3gw6A:20.40"],["4FUF_A_ACTA310_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3gw6","ENDO-N-ACETYLNEURAMINIDASE","Enterobacteria phage K1F",3,"GLN A 853;THR A 850;THR A 849","None","0.77A","4fufA-3gw6A:undetectable","4fufA-3gw6A:20.40"],["6H7J_A_5FWA401_0","BETA-1 ADRENERGIC RECEPTOR","3gw6","ENDO-N-ACETYLNEURAMINIDASE","Enterobacteria phage K1F",5,"ASP A 994;VAL A 996;SER A 848;ASN A 870;TYR A 857","None","1.22A","6h7jA-3gw6A:undetectable","6h7jA-3gw6A:12.77"],["6H7J_B_5FWB402_0","BETA-1 ADRENERGIC RECEPTOR","3gw6","ENDO-N-ACETYLNEURAMINIDASE","Enterobacteria phage K1F",5,"ASP A 994;VAL A 996;SER A 848;ASN A 870;TYR A 857","None","1.22A","6h7jB-3gw6A:undetectable","6h7jB-3gw6A:12.77"]]