SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 6 PHE A 200
ASN A 197
ILE A 135
GLY A 136
 None
 1.04A 1oniA-3gw7A:
undetectable
1oniB-3gw7A:
undetectable		 1oniA-3gw7A:
19.23
1oniB-3gw7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 6 PHE A 200
ASN A 197
ILE A 135
GLY A 136
 None
 1.12A 1oniD-3gw7A:
undetectable
1oniF-3gw7A:
undetectable		 1oniD-3gw7A:
19.23
1oniF-3gw7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 6 SER A 108
ALA A  77
THR A  81
ALA A  54
 None
 0.95A 1w0gA-3gw7A:
undetectable		 1w0gA-3gw7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 6 THR A 184
THR A 176
HIS A 173
LEU A 132
 None
 1.15A 4pgfA-3gw7A:
undetectable		 4pgfA-3gw7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.98A 5sxqA-3gw7A:
undetectable		 5sxqA-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.96A 5sxqB-3gw7A:
undetectable		 5sxqB-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.93A 5sxtA-3gw7A:
undetectable		 5sxtA-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.92A 5sxtB-3gw7A:
undetectable		 5sxtB-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.96A 5syjA-3gw7A:
undetectable		 5syjA-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 8 GLU A 155
VAL A 223
LEU A 179
THR A 176
 None
 0.95A 5syjB-3gw7A:
undetectable		 5syjB-3gw7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 6 SER A 108
ALA A  77
THR A  81
ALA A  54
 None
 0.94A 6ma6A-3gw7A:
undetectable		 6ma6A-3gw7A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 3gw7 UNCHARACTERIZED
PROTEIN YEDJ
(Escherichia
coli) 		4 / 7 SER A 108
ALA A  77
THR A  81
ALA A  54
 None
 0.94A 6ma7A-3gw7A:
undetectable		 6ma7A-3gw7A:
14.47